Celebrate the 4th of July! Be informed - it's patriotic. Check out an awesomely funny video from Prescription for Change. The colorful cartoon comes complete with singing and dancing prescription drug capsules, accompanied by the seriously screwed-up patients who popped pills with abandon and are now suffering the horrible consequences. (Male lactation, anyone?)

Prescription for Change is a public awareness-raising project funded by the powerful nonprofit Consumers Union. The vid's purpose: to raise awareness about inadequate prescription drug regulation in the US and to recruit public support in pushing for change. Specifically, it's about rallying support for the drug safety bill (HR2900) now before the US House of Representatives. It's not too much to ask, surely, that prescription medications be safe and affordable, and that information about drug side effects be fully explained to patients.

Diabetics be aware: a major case in point, illustrating Prescription for Change's critique of the status quo, is the Avandia scandal. The US Food and Drug Administration (FDA) failed to alert the public that Avandia, the Type 2 diabetes drug, manufactured by GlaxoSmithKline, increases the risk of heart attack. Oops.

View the cartoon by visiting YouTube. Or click here to visit the Prescription for Change website, which also features additional information about why reform is needed. You can also send an email to your Representative in support of the changes. Can Prescription for Change make a difference? Stay tuned.

Overeating can shut down a natural brain function that is key to preventing common cardiovascular and diabetic diseases..

Researchers found that chronic overeating can overwhelm the neural pathway that regulates the amount of fats flowing into the bloodstream from the liver. The liver is partly responsible for regulating fats entering the blood stream. It produces triglyceride fats the body can turn into LDL (bad) cholesterol, which can cause arteriosclerosis and blood vessel blockage. Glucose can enter the brain when levels are elevated in the bloodstream. When glucose enters the brain, it is broken down into an acidic substance known as lactate. Lactate signals the liver to stop making fat. It appears that chronic overeating can overwhelm the brain's ability to metabolize glucose into lactate. When lactate is no longer produced -- the signal to stop the liver from releasing fat into the blood stops, too. As small arteries get clogged, they create the circulatory problems common in type 2 diabetes, linked to overeating, obesity, and limb amputations.

Smaller portions, less glucose in the brain, better traffic flow. After all - nobody likes getting mixed signals. Let's do all we can to keep the lines of communimcation (and our arteries) open.

A new survey reveals that most people prefer to treat diabetes by changing their diets, rather than using medicines.

According to a survey of 1,022 adults (515 women and 507 men), 69% of Americans would prefer to try a dietary approach, whereas only 21% preferred treating diabetes with medicines. The survey reinforces results from clinical research on diabetes, which has consistently found that people with diabetes adapt well to low-fat vegetarian diets and gain important health benefits. A dietary approach to diabetes based on scientific research shows that a low-fat vegan diet can lower high blood sugar levels three times more effectively than oral medications.

Among the results: women are even more likely than men to prefer food changes over pills. People with more education and higher incomes were especially likely to favor a diet approach. For the financially savvy - this makes a lot of sense. You MUST buy food. You might as well buy healthier foods and curtail your Rx costs. Furthermore, Americans aged 45 to 64 were more enthusiastic about diet changes, compared with older Americans. I'll bet it's the convenience factor. A little less medication, a little more supper, please. The most pill-happy generation was the 18- to 24-year-olds. Don't look at me like that - I'm 28 and favor the flavor over medication, any day. Bon appetit!

USA TODAY ran a feature story that covered an American Diabetes Association, ADA, briefing over the weekend in which Robert Rizza, president of the ADA, stated that 7.2 million diabetic disabilities and deaths could be avoided by a simple daily pill that combined low-dose aspirin with drugs that lower cholesterol, blood pressure and blood sugar. A polypill is what Rizza called it.

Rizza went on to say that this treatment would cost approximately $100 dollars a year per person. According to the ADA, 21 million Americans have diabetes with an additional 41 million Americans at risk of developing diabetes. When I read this, it struck me that this is either a groundbreaking statement that has profoundly promising implications in the future treatment for diabetes -- or this is common knowledge in the diabetes community and then -- why is no one acting on this knowledge and developing the pill Rizza is referring to? Then again, is creating a mega-pill combining so many different medications in one pill -- prudent?

I am going with groundbreaking news, as the information shared in this weekend briefing was based on a mathematical model produced by Archimedes that predicts various outcomes based on variables in treatments. Now that they have this information, what will they do with it?

Vision loss is a real concern for diabetics. According to researchers, diabetics fear blindness more than they do death. The cause for potential vision loss due to diabetes results when blood vessels in the retina leak, and in a more severe stage, there is a profusion of fragile new blood vessels that form in the back of the eye that can leak.

In late-stage clinical trials, ruboxistaurin, an experimental drug developed by Eli Lilly, has proven effective in reducing vision loss caused by the effects of diabetes on the retina by 41 percent. The U.S. Food and Drug Administration has now agreed to review the research data in making a decision on whether to approve ruboxistaurin.

If approved, ruboxistaurin will be sold under the brand name Arxxant. As I understand what I am reading about this drug, it will be the first oral pill designed to slow or prevent vision loss. While the researchers were hoping the drug would slow progression of advanced vision loss, it appeared to be effective only in the early stages of diabetic retinopathy.