Not too long ago, I had the pleasure of speaking with David Kliff, of Diabetic Investor. When diabetes came knocking on David's door - he took the higher road, literally, and many would agree he has made the most of it.

David created Diabetic Investor to share his opinion as a leading authority on the business of diabetes from the unique perspective of a diabetic. Along the way he has gained interest in leading-edge technologies and breakthrough medicines to enhance the treatment of diabetes. His research and his craft for controlling his diabetes has significantly impacted his health for the best - and it keeps getting better.

David is now a marathon runner. His training efforts have resulted in a resounding 45 pound weight loss, cutting his insulin dose substantially, and improving his overall health. He launched a blog to promote his participation in the New York City Marathon this November. Checkout Dave's Run for Diabetes, and show your support for his efforts to go the distance for diabetes - all 26.2 miles!

Prior to the advent of insulin, in the 1920's, diabetes was treated with a low-carbohydrate diet. These diets were aimed at controlling sugar in the urine, a stark contrast to the current ADA suggested diet of low-fat and high-carbohydrate. In fact the diet recommended by Dr. Elliot Joslin consisted of approximately 20% protein, 75% fat and 5% from carbohydrates.

Well in the early century - this diet seemed to hold most diabetics on course just fine without the magic pills available today. It is also remarkable that the secondary complications and epidemic growth of diabetes was not a hot topic, either. Researchers decided to give Dr. Joslin's diet another go in a modern environment. The results of this low-carbohydrate ketogenic diet (LCKD) improved glycemic control in patients with type 2 diabetes such that diabetes medications were discontinued or reduced in most participants - 17 out of 21 completing the study. The original study had 28 participants, with 8 dropouts. The LCKD can be very effective at lowering blood glucose. Participants also experienced reductions in body weight, waist circumference, and body fat.

It's funny how this study, conducted in 2005, produced results seen almost 100 years prior. LCKD appears to be a reasonable cure for type 2 diabetes. If most diabetes was adequately treated back in days of 1923 without the assistance of pills and insulin - why is it such a mess nowadays? Where did we go wrong?

Ever wonder how Eli Lilly was able to get away with the Zyprexa scandal? A former member of the Lilly neuroscience team put it simply: statistics are like prisoners -- torture them long enough and they'll tell you what you want to hear. This YouTube video gives 6 jaw-dropping minutes of priceless pharmaceutical rep training on how to overcome sales resistance.

Quite remarkable is the coaching Lilly provided their pharmaceutical reps in dismissing the feedback they were receiving from doctors. Lilly told reps to ask doctors (in no uncertain terms) do you want a thin psychotic patient or a healthy fat patient? I think the operative word here is healthy. Does Lilly believe that excessive weight gain, insatiable hunger and Type 2 diabetes are healthy?

In Type 2 diabetes - the blood sugar rises, and spills into the urine, because the body resists insulin and resists its transfer of glucose out of the blood and into the cells of the body. The most important organ in the body – the brain – is protected by this insulin resistance. This is a protective reaction to prevent too sudden a fall in blood glucose, which can cause the brain to swell up with water! If too much glucose suddenly leaves the bloodstream the other sugars in the brain (sorbitol and fructose which are relatively unaffected by insulin) cause water to flow into the brain to correct the osmotic imbalance -- so the brain runs the risk of sustaining injury = too much sugar + too much insulin causes too much water.

Those of us who know what it's like to correct a high sugar with insulin know what it's like to feel bloated as our sugar comes down too quickly. The body is designed to protect its brain by only slowly reducing glucose in the blood and for any excess glucose to be flushed out in the urine. This is a temporary fix for a temporary carbohydrate overload. My billion dollar question is this: Have Lilly pharmaceutical reps been trained to dismiss the side effects of GM insulin (genetically modified to overcome insulin resistance) since it was first introduced in 1983? I'm curious how Lilly justifies diabetic complications.

Hear ye! Hear ye! I have an announcement to make. About 3 months ago, a committee formed to explore the possibility of creating a new conference series for adults with type 1 diabetes. Most conferences are currently geared towards all types of diabetes, but a group of us felt there should be more for the unique challenges that are posed to adults living with type 1.

With that in mind, we are conducting an interest study for the conference. Who would you like to see at the conference? Tell us what is missing from Type 1 diabetes (besides the obvious **cure**). This will help us with programming, as well as securing sponsorships for the event. Besides giving you all you want from the latest and greatest in type 1 diabetes - you have a chance to leave your mark on this revolutionary event. At the end of the survey, there is a question about creating a name for the conference. The committee will choose the winning name. The winner will receive an autographed copy of Know Your Numbers, by Amy Tenderich and Dr. Richard Jackson. The second and third places prizes are a Six Until Me mug and a Diabetes Mine mug, donated by Kerri Morrone and Amy Tenderich.

The survey closes on Friday, September 7, 2007 so don't miss your opportunity to voice your opinion. Take the survey today!!