What makes for a long and healthy life? Why, you say, how about a healthy diet and liberal quantities of exercise? True! A healthy lifestyle keeps you in shape and is one factor that promotes longevity. But have you ever wondered exactly how this works on a physiological level? How does the brain understand you skipped the gym all summer and had French fries for lunch yesterday?

The answer, according to the results of a new study published in Science (July 2007), could relate to insulin levels in the brain. Researchers induced lab mice to overeat until they became obese and some exhibited symptoms of diabetes. Yet some of those same mice actually lived eighteen percent longer than their slender mice buddies. The researchers attributed that longevity to a gene that affects insulin. Put simply: the longevity gene (called Irs2) effectively "tricked" the brains of those mice into thinking they were slim and fit, when in fact the opposite was true.

For diabetics, the study raises an additional question: if raising insulin levels decreases the body's sensitivity to it, is it really desirable to treat type 2 diabetics with insulin over the long-term? Lead author of the study, Morris White of Children's Hospital in Boston, says it's highly preferable (when possible) to get type 2 diabetes under control through old-fashioned diet and exercise, rather than through insulin or other meds.

I realize that I post often about the benefits of exercise and healthy eating, but until there is a cure for diabetes (and by cure I mean a real, honest-to-goodness cure and not some snake oil you can buy online from some dude in Guam) it is truly the best defense that people with diabetes have -- save for insulin (which, as all type 1s, 2s, and "3s" know, is not a cure, either). That all being said, I came across some quick tips on the Mayo Clinic Health Letter that offer up ways to help yourself eat less.

Apparently, there is research to back-up the fact that people eat less food when it is being eaten from a smaller plate. And with smaller forks and spoons (or "Sporks" if you're at KFC -- which you probably shouldn't be in the first place if you're trying to eat healthy, but...). The opposite of this effect also takes place when people eat from bigger bowls and plates; more food is consumed.

Lesson #1 Summary: Small plate/utensils, smaller caloric intake. Large plate/utensils, larger waistlines.

The Newsletter also suggested getting rid of high-calorie leftovers. That sliver of leftover birthday cake, the two slices of pizza from Domino's, the piece of apple pie from Easter -- either get rid of them or store them in opaque containers. If you see them, you will eat them. It's really as simple as that. So, in place of those sweets, have healthier, ready-to-eat options like nuts and Jello in plain site.

Lesson #2 Summary: You are what you eat, and you eat what you see.

The final tip in the newsletter is to buy small packages of food and, if possible, serve or order in small quantities. If you buy the Super-Jumbo-Massive-Gargantuan size bag of food, guess what? You'll probably end up eating a Super-Jumbo-Massive-Gargantuan amount of food. The easy solution is to purchase foods that come in smaller containers, which will automatically cause you to eat less and therefore consume less calories. Also, another trick is to serve the appropriate portions of a certain food and then put the leftovers away immediately. Don't leave them on the table, don't leave them on the counter, and definitely don't leave them on your plate. Back in the fridge they go -- out of sight, out of mind.

Lesson #3 Summary: Buying in bulk may sometimes result in, well, bulk.

Hats off to the folks at the Mayo Clinic for this one, because these are three ways to lose weight without going on a diet and/or performing even a minute of exercise. It doesn't get much easier than that!!

Each year the American Diabetic Association sponsors an informational campaign to promote healthy eating by providing practical nutrition guidance that focuses on the importance of developing sound eating and exercise habits. The theme for this year is 100 percent "Fad Free." The campaign features learning how to identify a food fad which is a food or diet fad that claims unreasonable or exaggerated benefits. If a diet or product advertises eating only specific foods, nutrient supplements or combinations of foods that may cure disease or offer quick weight loss, it is a fad. Diet fads come and go.

A balanced diet and physical activity are essential to a healthy lifestyle over the long term of your life. Develop an eating plan for the lifelong health. Choose foods sensibly by looking at the big picture because a single food or meal will not make or break a healthy diet. Find your balance between food and physical activity. Exercise does not have to be strenuous to be beneficial.

What increases bone density, promotes digestive health, helps keep kids healthy, and benefits the management of diabetes? Here's a hint, it sounds like the lifeblood treatment for type 1 diabetes - insulin - but the name of this goodie is inulin. Inulin in foods provides both bulk and sweetness without causing a rise in glucose levels.

Inulin is a natural dietary fiber found in over 35,000 common foods like artichokes, asparagus, onions, garlic, raisins and bananas. As an undigested fiber, it has no effect on blood glucose levels. It has a zero Glycemic Index. You could easily find it in your grocer's refrigerated section in Stonyfield Farm yogurts. Their version of inulin comes from chicory roots. Amazing all the places this ingredient naturally derives!

It is used increasingly in foods, because it has excellent nutritional and functional characteristics. Inulin can be used to replace sugar, fat, and flour. For the masses concerned with nutrition-labels, it contains one-third to one-fourth the food energy of sugar or other carbohydrates and one-sixth to one-ninth the food energy of fat. I'm curious to see what it tastes like, aren't you? From ignorant experience (uninformed of the artificial sweeteners used) I enjoy Stonyfield yogurts. I'll have to try another brand name with inulin on for size. Breaking news!! I just checked the ingredients in my newest dopamine-boosting fix: Trader Joe's low-glycemic dark chocolate. Golly gee-- sure enough inulin is on the list. I'm so in love with this dark chocolate because it really has such an insignificant affect on my blood sugar. Ultimate kudos to Ramsey, the creator of Miracle Muffins, for this sweet trinket of knowledge on artificial sweeteners!!

Pomegranate juice was shown to reduce the risk of arthrosclerosis in diabetics who participated in a study conducted over three months. The pomegranate juice also appeared to slow the absorption of unhealthy LDL cholesterol by immune cells.

People with diabetes have increased risk for atherosclerosis, contributing to coronary heart disease, heart attacks, strokes, and other circulation problems. The results of this study suggest that the antioxidants found in pomegranate juice may be beneficial in reducing these heart-related risks associated with diabetes. The sugars in pomegranate juice are attached to unique antioxidants, which actually make these sugars protective against atherosclerosis. Researchers examined the effects of drinking a concentrated pomegranate juice that is the equivalent to about a 6-ounce glass of freshly squeezed pomegranate juice for three months in 10 healthy adults and 10 adults with type 2 diabetes (who were not dependent on insulin therapy). Drinking pomegranate juice did not affect overall cholesterol levels, but researchers found it reduced the uptake of LDL (bad) cholesterol by immune cells, which is a major contributing factor to atherosclerosis.

Albeit a little tart, the reputation of the pomegranate falls heavily on the sweet side. One pomegranate delivers 40% of an adult's daily vitamin C requirement. Food manufacturers' favor using pomegranate extracts instead of the juice because it contains no sugar, calories, or additives. Factor in the folic acid, the free-radical destroying antioxidants, and the overall health benefits of the Chinese apple and ask your arteries if it's worth a 6 ounce glass. I'm guessing the answer is yes.

A clinical trial found the effects of a high sugar diet did not increase insulin resistance in the men tested. Insulin resistance is an important marker of diabetes risk. This study showed that an intake of sucrose two and a half times above average consumption did not have adverse effects on insulin resistance in healthy, nondiabetic men.

The study observed 13 healthy men over a 6 week period. The men ate either a high-sugar diet (25% of their energy from sugar) or a low-sugar diet (10% of their energy from sugar). After 6 weeks, the subjects crossed over to receive the other diet for another 6 weeks, separated by a four week wash out period during which the subjects returned to their usual diet. Insulin resistance was measured by a two-step glucose clamp. The high sucrose diet showed no significant adverse effects, such as elasticity of the arteries (known as vascular compliance) which impacts on risk of heart disease, and glycaemic profiles.

This study does not support the notion that sugar intake has any adverse effect on the risk of diabetes in healthy, nondiabetic men. Yes, I agree with the findings of this study. They are healthy. Their response to sugar is healthy. What would a study of 13 men with a parent who has type 2 diabetes look like? I suspect those results may show a horse of a different color.

Baltimore researchers from Johns Hopkins University have concluded a study indicating that being short -- specifically having short legs and a low leg length-to-height ratio -- is linked to an increased type 2 diabetes and obesity risk in middle age. It all goes back to childhood nutrition, as short leg length translates into the lack of proper nutrition during the formative years of physical growth.

According to the researchers, "Insofar as adult stature is an indicator of development and growth during early life, the risk of obesity and diabetes in adulthood might begin to accrue before puberty." They recommend early intervention to improve childhood nutrition in diabetes prevention.

This is observational on my part, and not the result of any study, but I do not believe this will apply to type 1 diabetes. My father-in-law was diagnosed with type 1 diabetes and he reached an adult height of 6-foot 4-inches. My sister-in-law was diagnosed with type 1 diabetes and she reached an adult height of 6-foot.