Yes, the title conjures up images of a futuristic world in which diabetics puff their way back to health. "New! Insulin Cigarettes!" In fact, it's rather more innocuous than that: scientists have engineered a type of insulin-containing tobacco plant that could - in theory, at least - be used as a diabetes treatment.

A study has just been completed of its use. Once freeze-dried and broken down into powder, the insulin-containing tobacco leaves were administered to mice. The scientists who came up with the plant (and who are based at the University of Central Florida), found the powder successfully prevented diabetes symptoms in the mice after eight weeks. It seems pretty safe to assume, they speculate, that humans with type 1 diabetes could get similar results from ingesting plant-based insulin.

The only snag so far is the image problem associated with tobacco. As a result, lead researcher Henry Daniell, is proposing a switch to lettuce, which is cheap, easy to grow and - oh, yeah! - is not associated with cancer. Good move.

The results of this study appear in the Plant Biotechnology Journal (July 2007).

The low-sugar watermelon is creating a big buzz in the news right now. The watermelon, developed by plant breeders at the US Department of Agriculture, contains less than half the sugar of regular melons. It may fit the bill perfectly for diabetics who crave a generous helping of that luscious summer treat. Brilliantly, beneficial concentrations of vitamin A, potassium and the antioxidant lycopene stay the same in the low-cal version. Don't rush to the local supermarket looking for it though: the seeds have only just become available to melon growers, so mature fruits has not yet hit the market.

The beauty of the low-cal melon is that it's all-natural. Okay, okay. It took some genetic engineering to get there. Still, noshing on a big stack of this watermelon has to be better for you than processed snacks and drinks, with their chemical cocktail ingredients list. Reports in today's news on the possible dangers of diet soda consumption, for example, might get people thinking harder about healthier ways to satisfy their sugar cravings. On the other hand, if you're not afraid of the artificial sweeteners, a sprinkling on the low-sugar melon will enhance the sweetness, sugar-free. Thank you, Mother Nature...and the USDA.

A study suggests problems with cholesterol regulation in the insulin-producing cells of the pancreas may be responsible for the development of Type 2 diabetes.

A thesis paper written by a graduate student, Dr. Liam Brunham, addressed the fact that a dysfunction in cholesterol regulation is found in beta cells in the pancreas. A thought-provoking connection to this thesis was the fact that beta cells are the cells responsible for producing insulin. A beta cell expert decided to see what would happen if researchers genetically engineered mice without the ABCA1 gene. The ABCA1 gene is the gene responsible for cholesterol regulation in beta cells. Dr. Brunham appears to be the first to identify the role of cholesterol dysfunction resulting in the beta cells inability to properly secrete insulin.

This new research is promising and obviously raises questions in other researcher's minds. One is - what happens when amylin, a hormone produced by the beta cells, builds up to excess amounts? Does this, in fact, impair the beta cells' ability to function properly? Could this be another thesis that trumps Dr. Brunham's hunch for the cause of type 2 diabetes? Some researchers believe that the over-production of amylin and cholesterol may be due to a yet unidentified problem. Of course that is always an option. Science labs across the world could come to a screeching halt if doctor's stopped hypothesizing. As research continues, we will anxiously await the next best thesis paper, courtesy of our promising Graduate Students. Be cool - stay in school!