Ever wonder how Eli Lilly was able to get away with the Zyprexa scandal? A former member of the Lilly neuroscience team put it simply: statistics are like prisoners -- torture them long enough and they'll tell you what you want to hear. This YouTube video gives 6 jaw-dropping minutes of priceless pharmaceutical rep training on how to overcome sales resistance.

Quite remarkable is the coaching Lilly provided their pharmaceutical reps in dismissing the feedback they were receiving from doctors. Lilly told reps to ask doctors (in no uncertain terms) do you want a thin psychotic patient or a healthy fat patient? I think the operative word here is healthy. Does Lilly believe that excessive weight gain, insatiable hunger and Type 2 diabetes are healthy?

In Type 2 diabetes - the blood sugar rises, and spills into the urine, because the body resists insulin and resists its transfer of glucose out of the blood and into the cells of the body. The most important organ in the body – the brain – is protected by this insulin resistance. This is a protective reaction to prevent too sudden a fall in blood glucose, which can cause the brain to swell up with water! If too much glucose suddenly leaves the bloodstream the other sugars in the brain (sorbitol and fructose which are relatively unaffected by insulin) cause water to flow into the brain to correct the osmotic imbalance -- so the brain runs the risk of sustaining injury = too much sugar + too much insulin causes too much water.

Those of us who know what it's like to correct a high sugar with insulin know what it's like to feel bloated as our sugar comes down too quickly. The body is designed to protect its brain by only slowly reducing glucose in the blood and for any excess glucose to be flushed out in the urine. This is a temporary fix for a temporary carbohydrate overload. My billion dollar question is this: Have Lilly pharmaceutical reps been trained to dismiss the side effects of GM insulin (genetically modified to overcome insulin resistance) since it was first introduced in 1983? I'm curious how Lilly justifies diabetic complications.

As Bev just pointed out, diabulimia is a serious condition when a type 1 diabetic is not taking their insulin in order to lose weight. Diabulimia is a term that has only cropped up in recent years. Most people who experience diabulemia are stuck between two fears: taking increasing doses of insulin, which leads to weight gain, and the damage the destructive behavior is causing their body in the long-term.

One expert who has studied the phenomenon estimates that 450,000 type 1 diabetic women in the United States - one-third of the total - have skipped or shortchanged their insulin to lose weight and are risking a coma and an early death. Ann Goebel-Fabbri, a clinical psychologist at the Joslin Diabetes Center in Boston says, "People who do this behavior wind up with severe diabetic complications much earlier". Is that supposed to be a warning or a promise? It sounds like she's saying complications are inevitable - but if you're contented with the weight gain - you'll deter the early arrival of complications. Poor advice, doc.

The caution of do as you're told and complications will arrive later is not a very promising guarantee. The behaviors of tight diabetes control are almost tantamount to cultivating eating disorders. Studies show that women with type 1 diabetes are twice as likely to develop an eating disorder. After all -- good diabetes management requires a preoccupation with food, counting carbohydrates and following a diet. Sounds like the ingredients for an eating disorder - throw in a hormonal imbalance (genetically modified insulin that arrives late to the brain, unlike natural vertebrate pork and cow insulin) and you've got yourself diabulemia. Thanks again, Big Pharma!! Where is the prize in good diabetes management if you are punished with weight gain?