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Posts with tag diabetic father

Diabetes may damage sperm cell DNA

A recent study compared the sperm of 27 men with type 1 diabetes to the sperm of 29 men of equal age without diabetes.

The researchers found that the sperm of the men with diabetes were healthy in many respects. The shape and abundance of the sperm from type 1 diabetic males were perfectly normal and apparently they were great swimmers. However, when the DNA was examined, there was more damage to the DNA of the diabetic men. Around 52% of the DNA in their sperm cells was fragmented, compared to only 32% in the men without diabetes. There was also a higher rate of deletions in the DNA inside their mitochondria, separate DNA found within each cell. The results of this study suggest type 1 diabetes may cause diabetic men to be less fertile.

However Diabetes Health recognizes that many type 1 dads have healthy children - so the study need not be a decision maker or breaker to pursue fatherhood. Thanks to Diabetes Health for reporting the ongoing pursuit of diabetes health.

Is Sugar the Culprit of Insulin Resistance?

A clinical trial found the effects of a high sugar diet did not increase insulin resistance in the men tested. Insulin resistance is an important marker of diabetes risk. This study showed that an intake of sucrose two and a half times above average consumption did not have adverse effects on insulin resistance in healthy, nondiabetic men.

The study observed 13 healthy men over a 6 week period. The men ate either a high-sugar diet (25% of their energy from sugar) or a low-sugar diet (10% of their energy from sugar). After 6 weeks, the subjects crossed over to receive the other diet for another 6 weeks, separated by a four week wash out period during which the subjects returned to their usual diet. Insulin resistance was measured by a two-step glucose clamp. The high sucrose diet showed no significant adverse effects, such as elasticity of the arteries (known as vascular compliance) which impacts on risk of heart disease, and glycaemic profiles.

This study does not support the notion that sugar intake has any adverse effect on the risk of diabetes in healthy, nondiabetic men. Yes, I agree with the findings of this study. They are healthy. Their response to sugar is healthy. What would a study of 13 men with a parent who has type 2 diabetes look like? I suspect those results may show a horse of a different color.

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