Prior to the advent of insulin, in the 1920's, diabetes was treated with a low-carbohydrate diet. These diets were aimed at controlling sugar in the urine, a stark contrast to the current ADA suggested diet of low-fat and high-carbohydrate. In fact the diet recommended by Dr. Elliot Joslin consisted of approximately 20% protein, 75% fat and 5% from carbohydrates.

Well in the early century - this diet seemed to hold most diabetics on course just fine without the magic pills available today. It is also remarkable that the secondary complications and epidemic growth of diabetes was not a hot topic, either. Researchers decided to give Dr. Joslin's diet another go in a modern environment. The results of this low-carbohydrate ketogenic diet (LCKD) improved glycemic control in patients with type 2 diabetes such that diabetes medications were discontinued or reduced in most participants - 17 out of 21 completing the study. The original study had 28 participants, with 8 dropouts. The LCKD can be very effective at lowering blood glucose. Participants also experienced reductions in body weight, waist circumference, and body fat.

It's funny how this study, conducted in 2005, produced results seen almost 100 years prior. LCKD appears to be a reasonable cure for type 2 diabetes. If most diabetes was adequately treated back in days of 1923 without the assistance of pills and insulin - why is it such a mess nowadays? Where did we go wrong?

Juan Domínguez-Bendala, Ph.D., is Director of Stem Cell Development for Translational Research at the Diabetes Research Institute. Once again, thanks to Gina and Jon at Diabetes Talkfest - you'll have the opportunity to chat live with Dr. Domínguez-Bendala on August 23rd at 9pm Eastern Standard Time.

Dr. Domínguez-Bendala is currently involved in several projects that focus on the use of embryonic stem cells to obtain pancreatic islets, in the hopes that these newly developed cells could one day be transplanted into patients with type I diabetes.

Join Dr. Domínguez-Bendala to discuss his work and ask questions pertaining to embryonic stem cell research. I know I'll be there, in true form, asking questions that I've been archiving for an event like this one!

Hear ye! Hear ye! I have an announcement to make. About 3 months ago, a committee formed to explore the possibility of creating a new conference series for adults with type 1 diabetes. Most conferences are currently geared towards all types of diabetes, but a group of us felt there should be more for the unique challenges that are posed to adults living with type 1.

With that in mind, we are conducting an interest study for the conference. Who would you like to see at the conference? Tell us what is missing from Type 1 diabetes (besides the obvious **cure**). This will help us with programming, as well as securing sponsorships for the event. Besides giving you all you want from the latest and greatest in type 1 diabetes - you have a chance to leave your mark on this revolutionary event. At the end of the survey, there is a question about creating a name for the conference. The committee will choose the winning name. The winner will receive an autographed copy of Know Your Numbers, by Amy Tenderich and Dr. Richard Jackson. The second and third places prizes are a Six Until Me mug and a Diabetes Mine mug, donated by Kerri Morrone and Amy Tenderich.

The survey closes on Friday, September 7, 2007 so don't miss your opportunity to voice your opinion. Take the survey today!!

Pfizer's bandwagon might be busted! Turns-out a study says inhaled human insulin, whether formulated as a powder or liquid, is more immunogenic than injected insulin.

Adverse effects of antibody formation have not been thoroughly investigated. But it was shown, comparatively, that inhaled insulin provokes more of an immune response than injections. Spitting is a dirty habit - but it's not good for nothing. The mucosal defense system is the body's primary line of defense against inhaled foreign matter - kind of like the MARINES of the human body. It is uniquely able to discern self from non-self bodies. So far - it looks like Pfizer's toker is a no go.

As I said before - the adverse events have not been thoroughly investigated. Until we know exactly what kind of mucosal revenge or pulmonary punishment lies ahead - I'd stick to the tried and true...subQ, for now. However the Generex Oral-lyn human trials are looking pretty promising. Stay tuned.

Ever wonder what would happen to a non-diabetic's blood sugar if they loaded up on a pile of concentrated sugar, preservatives and weird science fats? Doctors and the ADA call it prediabetes. This clip takes it to the extreme by sandwiching the center of 16 double stuff Oreos! Sometimes you have to be insanely blunt to make your point.

This is a brilliant example of the diabetes epidemic in action. In today's world -- many people are eating for convenience without realizing the consequences. More convenient equates to less nutritious - more preservatives, more sugar and even more fattening (the wrong fats, too!) The combination increases the amount of time our digestive enzymes need to work on these lab-derived ingredients. This sustains an elevated blood sugar following the time of consumption. Add the ADA definition of pre-diabetes (a blood sugar between 140 to 199 mg/dl 2 hours after a meal) and there you have it -- a potential player on Team Diabetes!

Think what would happen if this guy was in his doctor's office 2 hours after this stunt. I'd like to thank his employer for keeping him busy (whatever he's paid to do) well after the lunch hour - and protecting him from becoming another statistic. Big ups to HR for hiring this guy!! If he's not in marketing already -- you might consider a transfer and give this guy a raise. He's my Oreo hero.

Eli Lilly has an award they give to people who have been diabetic for 25, 50 and 75 years. They call it the Lilly for Life Award. The award recognizes people who have been enslaved to the exorbitant expenses of diabetes management, in addition to the other schedules of daily life. Endearing isn't it? The award is a significant token of Lilly's appreciation for all you have endured and sacrificed.

Lilly awards people who have used insulin for 25 years with the monetary equivalent of what your diabetes management has cost. All your copays for each bottle of insulin, each box of syringes, each blood sugar testing strip, and your ability to adapt to the ever-changing technology of diabetes care (I swear, it says that in block letters) - Lilly awards you $42,500!! I told you I lived in the land of milk and honey. ACTUALLY - it's a medal and a consent form to have your face exploited in Big Pharma marketing. You should've bought the stock! The shareholders of LLY paid approximately $1.75 per share 25 years ago, when you were diagnosed. Today that share is worth approximately $56. Anybody know the math on that return? It's probably around 3,000%.

Let's go back to that statement ever-changing technology of diabetes care. Why must it be ever-changing? Doesn't that sound a lot like never-ending? We need not spend too much time on identifying how to treat this disease when we've got that down. What we need to do is spend more time and energy on preventing the disease from happening in the first place. That is what I consider achievement. Achieve that, Lilly! And by the way - I'll take 3,000% of my $42,500 while you're at it. Thanks.

House Calls, a popular newsletter written by the prestigious Dr. Inglis, highlights a very important question in light of the Avandia mishap: how many other potential whistle-blowers are out there who have been silenced into submission before the Big Pharma vultures?

A medical expert testified that he agreed to sign a statement that was meant to appease the company's investors. This is not the type of behavior anyone should expect or dismiss of a doctor, entrusted with a patient's life. In his defense, he did forward a letter with his concerns to the FDA, which means they also were aware of the same threat. This same doctor is the President-elect for none other than the American Diabetes Association. Isn't that special? The ADA -- my friend, my confidant, my utter supporter of the C-peptide crusade ... sense the sarcasm? So much for advocacy, when the president-elect of this organization so willingly swept those safety concerns under the table, when he should have been throwing a tantrum on top of it! And all over the threat of litigation from a drug company more concerned about its investors than patients.

The closing comments in Dr. Inglis' newsletter say it all: There are so many vultures out there waiting to pick the bones of the American public, it disgusts me. This example goes to show why I always recommend to you -- and to all of my patients -- that you always question everything when it comes to your health. I don't care if it's your doctor you've had for 50 years or one of these nonprofit organizations -- give them all hell.

Have you heard about this online dating site specifically created for people with a health condition? Ricky Durham was inspired to create a site for his brother to meet people who battled with an illness that few people in the dating scene understood. Once Ricky saw how helpful it was for his brother - he opened it up for other people dealing with chronic conditions that would otherwise get in the way of breaking the ice.

These days, many people are seeking others online and consequently, specialized alternative dating services have emerged. Dating with a specific health condition can be awkward, especially when it comes time to divulge your situation, so an online service such as Prescription 4 Love could be just the outlet for you. Finding others with similar circumstances is a natural desire for everyone. Honesty is important, but finding an opportune situation to broach the subject can be difficult. By using Prescription 4 Love, you can be honest in advance and progress to the next stages of friendships and relationships.

Although the site was pioneered to meet the needs of Ricky's brother - he has since expanded the site to include many more conditions, including but not limited to: cancer, diabetes, obesity, IBS, allergies - and of course the more discreet conditions like HPV, herpes, and little people. As a commenter pointed out, little people is also the condition of dwarfism, a medical or genetic condition that usually results in an adult height of 4'10" or shorter, among both men and women. Wow. Thanks to the insight of a reader, I learned something new today!

If you've been around the diabetes online community you've certainly heard of Amy Tenderich. Her award-winning site is touted as one of the most influential diabetes sites out there. If you're looking for a gold mine of straight talk and encouragement -- Diabetes Mine is your destination. And now is your chance to speak to the celebrity herself! Amy will be chatting live on Tuesday, May 22, 9pm EST on Diabetes Talkfest.

Her charm comes through, loud and clear, in her cynically optimistic view of the trials of living with diabetes. Her journalistic flair derives from the heart and covers topics like breaking news and inside looks at diabetes research, as well as daily life with diabetes and uncovering the diabetics' deepest hopes and fears. Her all inclusive panache, along with her comedic nuances, make every moment of reading worth it.

Diabetes Mine has been featured in the Wall St. Journal, the UK Guardian, TechCrunch, NPR's Future Tense, and a number of other publications. The most recent feather in Amy's cap was added when she collaborated with Dr. Richard Jackson, a leading physician from Joslin Diabetes Center, to co-author the book Know Your Numbers, Outlive Your Diabetes. True to form, the book is hailed as the first-ever straightforward guidebook providing a clear strategy for living well with diabetes and avoiding the long-term health damage it can cause. I look forward to the opportunity of chatting with Amy. Hope you all can join us!

dLife is inviting all budding artists to send in their designs for its 2007 holiday cards. Up to 10 winning designs will be made into greeting cards to support the dLife Foundation's Holiday Cards for a Cause.

In addition to the bragging rights of being a contest winner, there will be 10 prizes awarded: 5 people will get a $100 Best Buy Gift Card and 5 people will get a $50.00 Best Buy Gift Card.

It's not hard to enter. Any non-professional artist is eligible - kids, teens, even adults. If you have diabetes or you have a loved one with diabetes and you would like to dedicate your work to them, you are free to enter. You can draw or submit any theme that you would like to see as a holiday greeting card. (Sorry, if you have ever received payment for any of your artwork, you are ineligible.). All artwork must be received by June 21, 2007 for consideration. See dLife for all the details of the contest. Thanks to Gina of Diabetes Talkfest for letting me display her card submitted for the contest - isn't it beautiful? Good job, Gina!!

In the next 3 to 5 years, we will have a new generation of control upon us providing continuous glucose monitoring. Some of these marvelous technologies will not require a drop of blood, while others will embody the tried-and-true stick-to-itiveness we all know and loathe.

Please join me as we browse the isles of things to come (and things now available) for continuous glucose monitoring.

The DexCom STS Continuous Glucose Monitoring System is a glucose sensor that reports glucose values every 5 minutes for up to 72 hours. The sensor is inserted in the abdomen. After a 2 hour start-up period, the STS System is calibrated with 2 fingerstick measurements taken by a traditional glucose meter. Checkout Amy Tenderich's review on Diabetes Mine of the DexCom Continuous Glucose Monitoring Sytem.

MiniMed Medtronic has 3 different versions: the Gold, the Guardian RT, and the Paradigm Real-Time Continuous Monitor.

Menarini GlucoDay S is a device worn by the patient for the continuous monitoring of glucose in the subcutaneous interstitial fluid. Monitoring is performed via insertion in the abdominal region of a microfibre for dialysis having the diameter of a human hair. Inside the microfibre a solution transports the patient's glucose to a biosensor within the instrument.

M-Biotech Glucose Biosensor is a minimally invasive implantation for painless and convenient monitoring. The key feature of our efficient Glucose Biosensor is the combination of a glucose-sensitive hydrogel and a miniature pressure sensor. Glucose-responsive hydrogels are biocompatible materials that either swell or contract when the glucose concentrations change in the body fluid surrounding the hydrogel.

The PreciSense System includes a microcapsule placement unit and a light detecting non-invasive reader unit. The microcapsule placement unit poses the right dose of glucose-responding microcapsules in the upper layer of the skin, painlessly. The glucose assay components in the microcapsules generate a fluorescence signal that corresponds to the glucose level. The non-invasive reader unit monitors this glucose binding event through FRET, Fluorescence Resonance Energy Transfer, which is directly related to the concentration of glucose.

Sensors for Medicine and Science glucose sensor is implanted under the skin in a short outpatient procedure. The sensor automatically measures interstitial glucose every few minutes, without any user intervention. The sensor implant will communicate wirelessly with a small external reader.

Synthetic Blood Implanted Glucose Biosensor claims to offer significantly more accurate glucose readings in a range of 30-500 mg/dl. The implanted Glucose Biosensor continuously monitors blood glucose without the need for finger sticks. The most accurate glucose monitor available, the implanted biosensor can be programmed to monitor blood glucose according to a predetermined schedule, thus eliminating problems of patient compliance. The sensor alarms for dangerous, life threatening conditions such as hypoglycemia.

GlucoLight Corporation is developing a low-cost non-invasive blood glucose monitor for home use by diabetic patents. GlucoLight's unique optical approach, microScatterTM (microscatter) technology, is based on patented technologies in the area of Optical Coherence Tomography (OCT) and Low Coherence Interferometry (LCI). There is a working prototype with published clinical data on healthy volunteers.

The GlucoWatch G2 Biographer was approved to detect glucose level trends and track patterns in people with diabetes. It must be used along with conventional blood glucose monitoring of blood samples. The device, which looks like a wristwatch, pulls body fluid from the skin using small electric currents. It can provide six measurements per hour for 13 hours. (See David Mendosa's review).

Once again Diabetes Talkfest is making the experience of diabetes rewarding. This time, voice your funny in iambic pentameter and you can win an iPod Shuffle. In other words -- the funniest diabetic poem wins a REALLY COOL PRIZE!!!

Your poem can be long or short, rhyme or not. If you submit a poem longer than 60,000 characters it will have to be done in multiple posts, as the message board will not accept posts that long. It is up to you -- the member -- to decide the winner (to be decided through an anonymous vote).

Entries will be accepted during the month of May, 2007. Voting will begin June 1st, 2007 and end June 18, 2007.

Please refrain from using profanity or obscene language. Please don't insult anybody. Diabetes Talkfest is a family site. Any entry that is determined to be obscene or off-topic will be deleted. Please do not submit anything you did not create on your own. We can't accept copied or copyrighted work.

All participants must be registered to enter the contest. Thanks to Gina and Jon for keeping the spirit of community alive in the diabetes online community!

Mike Huckabee is a politician, an award winning "Health Crusader", and a successful loser of over 100 pounds.

After being diagnosed with type 2 diabetes in 2002, his doctor gave him two oral meds and a stern warning. His doctor told him the condition of his health, the lifestyle he leads and the stress level of his job would likely put him six feet under within 10 years. At 48 years of age he was one of the youngest governors in the Nation. He knew he could win this fight -- and he did. After losing 110 pounds, the Governor of Arkansas reversed his diabetes and serendipitously assumed a role in the war against obesity.

It took a sobering message, dedication and commitment to bring Mike the healthy lifestyle he enjoys today. On the next dLifeTV, learn how Governor Mike Huckabee is winning the battle against diabetes. dLifeTV airs every Sunday on CNBC at 7PM Eastern, 6PM Central and, 4PM Pacific.