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Posts with tag cells

Seaweed-coated implants work, say Johns Hopkins researchers

In the past, I've blogged about an Australian experiment using implants that could, theoretically, eliminate the need for type 1 diabetics to use insulin shots. Researchers said it's possible to implant seaweed-coated capsules containing insulin-producing cells in the abdomen. The cells produce insulin, but the tiny pores in the seaweed do not allow immune system cells to pass through and destroy the cells. Allie has also looked at a related issue: experiments that surgically attach kelp-coated islets to the liver for the same purpose.

Sounds pretty brilliant. But could it really work? The verdict looks like "Yes." According to the results of a new Johns Hopkins University study, such implants could be helpful for type 1 diabetics whose bodies otherwise reject insulin transplants. The capsules utilized in the study were coated with a substance made from alginate, which is derived from seaweed. The technology could eventually be offered to diabetics whose bodies reject insulin cell transplants, something which could became standard treatment in the future. It would likely be a safer choice than the only other option known so far: anti-rejection drugs. Talk about the power of nature!

The results of the study have been published in Nature Medicine. Next step is a larger trial that will lead to seeking FDA approval for the technique.




Zinc Does Not Prevent Diabetes

Despite claims by zinc supplement manufacturers that the pills can help prevent type 2 diabetes, clinical trials do not support this hypothesis.

Laboratory research suggests that zinc helps promote the production and action of insulin. A four-week study of 56 obese women found that zinc did not have an effect on factors associated with the development of diabetes. This study was an example of one trial that treated 56 people with either zinc or a placebo for four weeks and found no effect. This single trial is too small and too short to tell us anything about the effectiveness of zinc in preventing the development of type 2 diabetes.

Research does support that zinc plays a key role in the regulation of insulin production and glucose utilization. Diabetics have shown a zinc deficiency, which impairs their ability to use glucose. However this fact does not confirm zinc as a supplement to prevent the development of diabetes. I apologize it's a nonevent insofar as news. But look at it this way – it's one trial. Nobody says you have to cross it off your list because 56 obese women didn't see a change in their risk factors for developing diabetes. One study is not gospel.

Pomegranate Helps Diabetic Hearts

Pomegranate juice was shown to reduce the risk of arthrosclerosis in diabetics who participated in a study conducted over three months. The pomegranate juice also appeared to slow the absorption of unhealthy LDL cholesterol by immune cells.

People with diabetes have increased risk for atherosclerosis, contributing to coronary heart disease, heart attacks, strokes, and other circulation problems. The results of this study suggest that the antioxidants found in pomegranate juice may be beneficial in reducing these heart-related risks associated with diabetes. The sugars in pomegranate juice are attached to unique antioxidants, which actually make these sugars protective against atherosclerosis. Researchers examined the effects of drinking a concentrated pomegranate juice that is the equivalent to about a 6-ounce glass of freshly squeezed pomegranate juice for three months in 10 healthy adults and 10 adults with type 2 diabetes (who were not dependent on insulin therapy). Drinking pomegranate juice did not affect overall cholesterol levels, but researchers found it reduced the uptake of LDL (bad) cholesterol by immune cells, which is a major contributing factor to atherosclerosis.

Albeit a little tart, the reputation of the pomegranate falls heavily on the sweet side. One pomegranate delivers 40% of an adult's daily vitamin C requirement. Food manufacturers' favor using pomegranate extracts instead of the juice because it contains no sugar, calories, or additives. Factor in the folic acid, the free-radical destroying antioxidants, and the overall health benefits of the Chinese apple and ask your arteries if it's worth a 6 ounce glass. I'm guessing the answer is yes.

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