Pfizer's bandwagon might be busted! Turns-out a study says inhaled human insulin, whether formulated as a powder or liquid, is more immunogenic than injected insulin.

Adverse effects of antibody formation have not been thoroughly investigated. But it was shown, comparatively, that inhaled insulin provokes more of an immune response than injections. Spitting is a dirty habit - but it's not good for nothing. The mucosal defense system is the body's primary line of defense against inhaled foreign matter - kind of like the MARINES of the human body. It is uniquely able to discern self from non-self bodies. So far - it looks like Pfizer's toker is a no go.

As I said before - the adverse events have not been thoroughly investigated. Until we know exactly what kind of mucosal revenge or pulmonary punishment lies ahead - I'd stick to the tried and true...subQ, for now. However the Generex Oral-lyn human trials are looking pretty promising. Stay tuned.

Who would've thought that the same company who gave rise to Super Mario Brothers would transform a generation into virtual athletes? And I know what you're thinking - don't even try to turn this video gaming habit into a banner health campaign. Hold the phone, sister. Read on and you'll see what Nintendo has done.

The calorie-carnage begins with a wireless remote -- like a piece of sporting equipment. In fact this wireless piece is your symbolic tennis racket, baseball bat or golf club. Players use the momentum of their body movements to engage a sensor placed on top of the television. The freebie games that come with Nintendo Wii are: tennis, golf, baseball, and even boxing. Of course the games to choose from are as far as the imagination can stretch. You can even pay to download the good old games like Super Mario Brothers and other hits from back in the day. The gaming actively involves movement of the biceps, shoulders, core and even the legs. All of this, of course, happens in the comfort and privacy of home, which means users of any age or skill level can hit the virtual court, diamond or links anytime.

In a study of 25 kids 8 to 12 years old, researcher Lorraine Lanningham-Foster at the Mayo Clinic in Minnesota, found that kids playing active video games (Sony's EyeToy and Konami's Dance Dance Revolution Ultramix 2) expended roughly double the energy of kids playing sedentary video games.

Wii has attracted a devoted following, including 26-year-old Mickey DeLorenzo, of South Philadelphia. The multimedia developer quickly attained cultural hero status by blogging the results of his 30-minute-a-day Wii exercise regimen. DeLorenzo, who lost 9 pounds between Dec. 3 and Jan. 15 just by playing Wii games.

If you're still curious what the game looks like in action take a moment to watch a crafty commercial Nintendo put together. The theme of the commercial is: Wii would like to play. Enjoy!

Diabetes Mine's Amy Tenderich is blogging the American Diabetes Association's 66th Annual Scientific Sessions. While Richard Kahn, Chief Scientific & Medical Officer for the American Diabetes Association is blogging the same convention, Tenderich promises to give her readers the uncensored and totally unofficial scoop. I believe she will more than deliver on her promise.

I am certain everyone in the online diabetes community is well aware that Tenderich blogs the Diabetes Mine, but if you are new to diabetes and reading this, her blog is a must visit. Amy -- diagnosed with Type 1 diabetes three years ago -- is all-things-real with the intelligence and sharp commentary to back it up. A most excellent blogger and blog.

Kerri Morrone, one of my favorite bloggers -- who happens to be living with diabetes without allowing it to define the life she lives -- blogs over at Six Until Me. She also writes a column at dLife, and her latest column Diabetes Can be a Day at the Beach: Integrating Your Pump Into the Summer Season is a reassurance that integrating the pump into summer wear isn't nearly as daunting and formidable a task as one might imagine before making the attempt. Perhaps a little trickier and requiring a little more ingenuity, than say, wearing the pump under layers of winter clothing might require -- but she shows how it can be done, and done well.

Morrone also shares the sometimes amusing and less than astute observances made by the general public. There are, of course, the experts who wander among us, who know everything. Just ask them about anything and they will clarify exactly what you are looking at but might not understand. You will see what I mean after you read Morrone's column. What a pinhead the guy was -- that's all I am going to say. To read her column, go here.