You've heard about the sports stars and the rock stars who succeed in life despite suffering from diabetes. Now, here's something a little more unusual: a circus acrobat! Dolly Jacobs is Circus Sarasota's "Queen of the Air." She recently gave an interview to the Bradenton Herald about her life in the circus.

Trim and petite like a dancer, Jacobs was diagnosed ten years ago. How did it happen? She had the warning signs most type 1s experience: weight loss and a killer thirst she just could not quench. Her mom already had type 1, so during a routine office visit, Jacobs asked the doc to check her blood sugar too. Whoa. It was 260 - way, way above normal. Jacobs was diagnosed not with type 1, but with a rarer form sometimes dubbed "type 1.5" or Latent Autoimmune Diabetes of the Adult (LADA). LADA is basically the same as type 1 diabetes, but develops later in life.

So how does one deal with diabetes when your job involves flying through the air with the greatest of ease? Low blood sugar is easy, says Jacobs. Correct it with a soda or juice. High blood sugar is tougher. She says she can go as high as 500 or 600 just from adrenaline. So, just like any other athlete, she depends on testing several times daily and she wears an insulin pump - but not when she's performing. Eating healthy - lean meats, fruits and veg - are important too, she says.

Click here to read more. Kudos, by the way, to the journalist who wrote this article, Roberta C. Nelson, for taking time out to identify the different forms of diabetes and to explain the dangers associated with high vs. low blood sugar. Great!

Circumstances of confusion invalidated a Diamyd clinical trial to protect insulin-producing cells in diabetes patients. This confusion amounts to a speed bump, but Diamyd intends to press on.

The company admitted that the Phase II clinical trial of its gene therapy had been botched following a mix up over which patients received the drug and which got placebo. Diamyd is a vaccine based on GAD65, a major factor for diabetes due to an autoimmune reaction. The company designed the vaccine to reduce the need of insulin injections and prevent the destruction of beta cells that produce insulin in the pancreas. Also, by protecting these cells, it may allow them to regenerate in a non-autoimmune environment, and possibly set the stage for a cure of the disease.

Anders Essen-Möller, CEO of Diamyd, said: "Was the drug mixed up? We do not know. Could there be a mix-up at some other times in the study? Yes it is possible, but that is not certain." Essen-Möller is determined not to let the mistake ruin the vaccine's progress towards approval. Essen-Möller also said he believes that the invalidation of the trial will not adversely affect any ongoing meetings with potential partners.

Just like a referee to normalize play throughout the game - DiaKine Therapeutics is developing ways to normalize the body's immune system.

The new drugs modulate cytokines, part of the body's immune system, which mistakenly attack normal organs and tissue and cause diseases such as: diabetes, multiple sclerosis and inflammatory bowel disease. Research by Dr. Nadler and his collaborators published in 2006 showed that controlling certain cytokines can arrest the progression of, or reverse, type 1 diabetes in an animal model.

The company's first product, IsletLifeLSF Media 1 is designed to improve the viability and insulin producing capabilities of harvested islet cells prior to transplant. This would potentially improve the success rate of the procedure. Additional therapeutics under development by DiaKine include: adjunct therapy to islet cell transplants, halting the progression of type 1 diabetes in newly diagnosed adults, treatment and prevention of Latent Autoimmune Diabetes of Adults (LADA), treatment and prevention of insulin requiring type 2 diabetic, treatment and prevention of diabetes complications.

It all sounds like good stuff in the works. Keep an eye on the progress and press releases of DiaKine, as well as their research partner - the Diabetes Research Institute. A lot is happening these days. What else have you seen or heard about in the autoimmune arena?