The beta-blocker carvedilol does not cause weight gain in diabetic patients, declares a new study just out. Significance? It means the drug does away with a problematic side-effect of other (earlier) beta-blockers, which are medications prescribed to correct high blood pressure. The study has been published in the American Journal of Medicine (July 2007) and was conducted by researchers at St. Luke's-Roosevelt Hospital Center in New York.

Around eleven hundred patients participated in the study, all of whom have Type 2 diabetes and also suffer from high blood pressure. Some took the new drug carvedilol, while others were given the standard metoprolol. Over the course of five months the patients on metoprolol gained an average of 1.19 kg/2.6 lbs, whereas those on taking carvedilol experienced an average gain of 0.17 kg/0.37 lbs, which is considered insignificant.

Weight gain is an undesirable side-effect of medications in virtually any circumstance. However, it is particularly true for people with Type 2 diabetes or those at risk for T2 because overweight and obesity contributes to insulin resistance. In other words, weight gain will likely increase your chances of developing T2 if you're already predisposed or it will make your T2 worse if you already have it...putting you more at risk for the kinds of heart problems that beta-blockers are prescribed to treat! So it's no surprise that Franz H. Messerli, the lead author of the study, told Reuters that doctors should "avoid traditional beta-blockers such as atenolol and metoprolol in the diabetic hypertensive patient or in the hypertensive patient at risk for diabetes."