Note: The contents of this blog are for informational purposes only and should not be construed as medical advice or substitute for professional care. For medical emergencies, dial 911!
Posts with tag DiabetesDiscoveries
Posted Aug 15th 2007 11:41PM by Allie Beatty
Filed under: Type 1, Childhood, Research, Blogs, Products, Bloggers, Personalities, Form and Function
For those of you who do not know her yet - consider today your lucky day!! She is Amy Tenderich and her site, Diabetes Mine, is a force to be reckoned with in the diabetes online community. What do I mean? When Amy speaks - anybody who's anybody in the diabetes online community listens.
A few months ago she posted an open letter to Steve Jobs, which was wildly discussed in the blogosphere and media. She invited gadget designers to rise to the challenge of creating sleeker, cooler, consumer-oriented medical devices for people with diabetes. Not only did she get the diabetes blogosphere stirring - but the minds of entrepreneurs storming, as well.
Amy motivated a San Francisco-based company to react in a universal remote control sort of way. Adaptive Path has designed The Charmr, a prototype of a continuous glucose monitor combined with an insulin pump, universally controlled by a device that looks to be no bigger than a USB stick! I strongly encourage everybody to checkout Amy's blog with all the details (including reader feedback) and the YouTube video on the Charmr. Bravo Amy!!
Posted Aug 10th 2007 9:18AM by Allie Beatty
Filed under: Type 1, Childhood, Drugs, Research, Allie Beatty
The scientific community has been in a heated debate about xenotransplants (transplanting pig islets into humans). Although the procedures are showing to be effective - is the insulin secretion entirely pig? Some experts surmise that after the transplants, diabetic patients are actually able to produce some insulin on their own, after all.
The latest press release from Tissera, Inc (an Israeli-based company) made a statement that raises my hopes. It was, "By the fourth month after transplantation, the insulin dose needed to maintain near-normal blood sugar levels decreased by more than 90% in comparison with the insulin dose needed before transplantation, meaning that endogenous insulin production was predominantly responsible for blood sugar control."
The question of the origin of endogenous insulin was addressed by measurement of blood C-peptide. C-peptide splits from insulin and indicates the level of insulin secretion from the patient. C-peptide levels were measured both at baseline and in response to a sugar load, which brings about a rise in blood C-peptide. The measured C-peptide was shown to be predominantly of pig origin. So herein lies my question: is predominantly more than 50%? A type 1 diabetic has undetectable levels of C-peptide. Period. After the xenotransplant the C-peptide level is all of a sudden detectable? Could these islet transplants assist in regenerating the diabetics' own islets?
