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Posts with tag DiabetesBlindness

Average blood glucose instead of HbA1c

Change appears to be coming for diabetes care. The HbA1c test may not be the safest approach for diabetics to follow in preventing complications. Instead, experts are saying the average blood glucose level per individual will add clarity to diabetic patients looking to manage their disease.

A study supporting the change showed a close correlation between average glucose and HbA1c levels. So the myth, busted is: maintaining an average blood sugar is a safer approach for diabetes management -- NOT CHASING A UNIFORM HbA1c value. The fluctuation in blood sugar is what causes complications in the small vessels of the eyes, kidneys and peripheral nerve endings. For example - sustaining a blood sugar of 200 mg/dL is a lot safer than waking at 240 and ushering a boatload of sugar into your cells to drop your sugar to 80 mg/dL. It is the transfer of glucose into the cell that causes the injury to cell membranes and resulting complications.

Think of it like the movement of the ocean. High tide to low tide happens gradually, over the course of many hours throughout the day. When a storm hits - the waves become turbulent, crashing against the shore causing erosion. Is the human body any different? I'm not a doctor -- but I did stay at a Holiday Inn Express last week.

Diabetes Complications - the White Elephant

A white elephant is a supposedly valuable possession whose upkeep exceeds its usefulness, and it is therefore a liability. Every type 2 diabetic is a valuable possession to someone: a mother, a father, a sister, a brother, a daughter, a son...you get the picture. But when it comes to the complications of the disease - it costs the U.S. health system an extra $22.9 billion a year to treat these complications.

"It is a pretty significant wake-up call for people, or should be. It really points out the importance of managing the disease," said Willard Manning, a health economist at the University of Chicago who worked on the report.

Dr. Daniel Einhorn says "the fact that people are still getting complications means we are not using our tools effectively enough," When people fail to follow their diet, exercise and drug treatment plans, the disease leads to complications that boost the total health bill to $57.1 billion. "Either the patient doesn't recognize they have it and complications develop, or they are not good about adhering to their doctor's orders," he said, adding, "We've got to do a better job of managing the disease." Dr. Einhorn serves on the board of the American Association of Clinical Endocrinologists.

Of course, it's the patient -- NOT the drugs they are using. It couldn't possibly be the drugs.

C-Peptide - Missing in Action

When treating diabetes, today's doctors focus on establishing blood glucose control, but often overlook the need to protect against common diabetic complications such as blindness, kidney damage, and nerve damage. The DCCT, even with a comprehensive treatment program, had a complication rate of approximately 40% of participants.

People who do not have diabetes make insulin with C-peptide. Those of us diabetics who inject synthetic insulin do not get the C-peptide. When scientists began developing insulin - they weeded out the pieces of the amino acid chain they felt were insignificant in lowering blood glucose. Synthetic insulin was designed to reduce the dangerous buildup of excess sugar in the bloodstream. Uh oh - hindsight is surprisingly clear! The long-term complications were initially thought to be caused by lack of insulin - not lack of something that should've been in it. It would make sense if insulin came equipped with this critically important element, wouldn't it?

Tada! C-peptide is the connecting peptide found on the amino acid chain of naturally produced insulin, but left on the cutting room floor in the lab. Studies have shown that C-peptide prevents the development and progression of many diabetic complications and was shown to improve glucose metabolism up to 66%.

Regardless of the potential profit decay C-peptide might cause the production of insulin - the bottom line is the salvation it will provide every man, woman, and child injecting insulin. If you're taking insulin injections, chances are you won't stop taking insulin because you're adding C-peptide to your daily lineup. Chances are - you'll be around a lot longer, and a lot healthier because you do not have the complications most often associated with long-term diabetes.

Wouldn't that be reason enough for you to celebrate the company that brings C-peptide to the drugstore nearest you? Consumer loyalty goes a long way. For those companies who knew a long time ago how beneficial C-peptide would be but didn't do a thing about it - is it really the 33% loss in insulin sales you didn't want to encounter? C'mon. We can handle the truth.

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