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Posts with tag Cure diabetes Now

Bicycling to bring a cure closer

In two weeks, Bernard Farrell will be riding in the Bike the Miles annual fundraiser to support Dr. Faustman's research to cure Type 1 diabetes. His participation is especially intrinsic because it is one day away from his 35th anniversary of becoming a Type 1 diabetic.

Bernard plans to raise $10,000 for Dr. Faustman's research. Last year he raised $7,500. The entire event raised a whopping $301,000! All of this funding is going toward the human trials to cure Type 1 diabetes. After discovering that the insulin-producing islet cells of the pancreas are capable of regeneration, Dr. Faustman now needs to test her treatment, already known to be safe in humans, to see if the effects are as positive as they were in the animal model.

It goes without say that this is terribly important for Bernard as much as it is for every man, woman and child touched by Type 1 diabetes. Bike the Miles is an annual event that was started by Susan Root and Jacqueline Fusco in 2004. Both, Susan and Jacqueline, have children who are Type 1 diabetics. Please visit Bernard's site to support his ride and the drive to cure Type 1 diabetes!

Diabetes Talkfest live chat with stem cell researcher

Juan Domínguez-Bendala, Ph.D., is Director of Stem Cell Development for Translational Research at the Diabetes Research Institute. Once again, thanks to Gina and Jon at Diabetes Talkfest - you'll have the opportunity to chat live with Dr. Domínguez-Bendala on August 23rd at 9pm Eastern Standard Time.

Dr. Domínguez-Bendala is currently involved in several projects that focus on the use of embryonic stem cells to obtain pancreatic islets, in the hopes that these newly developed cells could one day be transplanted into patients with type I diabetes.

Join Dr. Domínguez-Bendala to discuss his work and ask questions pertaining to embryonic stem cell research. I know I'll be there, in true form, asking questions that I've been archiving for an event like this one!

Xenotransplants - the pig or not the pig

The scientific community has been in a heated debate about xenotransplants (transplanting pig islets into humans). Although the procedures are showing to be effective - is the insulin secretion entirely pig? Some experts surmise that after the transplants, diabetic patients are actually able to produce some insulin on their own, after all.

The latest press release from Tissera, Inc (an Israeli-based company) made a statement that raises my hopes. It was, "By the fourth month after transplantation, the insulin dose needed to maintain near-normal blood sugar levels decreased by more than 90% in comparison with the insulin dose needed before transplantation, meaning that endogenous insulin production was predominantly responsible for blood sugar control."

The question of the origin of endogenous insulin was addressed by measurement of blood C-peptide. C-peptide splits from insulin and indicates the level of insulin secretion from the patient. C-peptide levels were measured both at baseline and in response to a sugar load, which brings about a rise in blood C-peptide. The measured C-peptide was shown to be predominantly of pig origin. So herein lies my question: is predominantly more than 50%? A type 1 diabetic has undetectable levels of C-peptide. Period. After the xenotransplant the C-peptide level is all of a sudden detectable? Could these islet transplants assist in regenerating the diabetics' own islets?

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