You don't even need a prescription for this one. Nutrition 21, Inc., a nutritional bioscience company, markets drugstore supplements such as selenium and omega-3 fish oil. They recently announced new published results of a clinical study of their patented product Diachrome(R), a combination of chromium picolinate and biotin (a B vitamin).

Here's the skinny on the study. In a 447 subject, randomized, double-blind, placebo-controlled study, type 2 diabetics taking Diachrome(R) realized significant improvements in glycemic control (an absolute decrease in A1C of 0.54%). More dramatic decreases were seen for type diabetics with terrible glycemic control levels (A1C levels equal or greater than 10%). These diachrome(R)-takers saw an additional absolute A1C decrease of 1.76%, and they were already taking one or more prescriptions to treat their type 2 diabetes. Improvements were also seen in fasting glucose levels and triglycerides to high density lipoprotein (HDL) ratios.

Is a nutritional supplement honestly going to help people with type 2 diabetes? I checked out the Diachrome(R) website and found the product has been around at least since 2004, possibly even longer. The FDA has deemed it safe. Perhaps it does enhance insulin function, but the website clearly states it should never replace medications already being prescribed to treat type 2 diabetes.

Chromium picolinate is one of the most widely debated supplements in diabetes health. A study has shown that it improves glycemic control in patients with type 2 diabetes not adequately controlled while taking sulfonylurea, a drug that increases insulin release from the beta cells in the pancreas.

A 40-week study was designed to examine the effect of adding daily chromium picolinate supplementation to an antidiabetic medication, sulfonylurea. A commonly prescribed treatment for type 2 diabetes was given to 29 subjects for 24 weeks, in conjunction with either chromium picolinate or a placebo. Blood sugar levels of study participants taking chromium picolinate dropped significantly compared to the placebo group. In addition, insulin sensitivity for participants taking the chromium picolinate was increased when compared to those in the placebo group. Study participants taking chromium picolinate also experienced significantly lower abdominal body fat accumulation than the placebo group, and experienced less overall weight gain.

This study demonstrates that chromium picolinate supplementation for type 2 diabetes who are taking sulfonylurea agents significantly improves insulin sensitivity and glucose control. In addition, chromium picolinate was shown to reduce weight gain and fat accumulation compared with the placebo group. The results of this study were first published in August 2006 - but knowing about chromium picolinate today leaves you with ample time to adjust for greater insulin sensitivity and less fattening days to come!

Do you ever wonder if there's a trick to getting this diabetes thing down? Well I did. Like many fellow surfers, I asked Google for diabetic tricks. Not surprisingly, Google had a litany of answers. You may have heard about them before and most of us dismiss supplements as nothing more than snake oil. However, supplements are gaining credence when it comes to cutting risk and alleviating symptoms of type 2 diabetes. Take a look...

Chromium picolinate. Taking 200 to 1,000 micrograms daily can lower blood glucose, improve insulin function and lessen diabetic symptoms such as thirst and fatigue, says expert Richard Anderson, Ph.D., of the U.S. Department of Agriculture. In recent Israeli research, taking 200mcg twice a day for three weeks reduced diabetics' blood glucose by 26% and cholesterol by 9%. Anderson advises all adults to take 200mcg chromium picolinate daily to help prevent diabetes. New studies have put old safety questions to rest.

Cinnamon. The spice boosts insulin's efficiency in processing sugar, Anderson says. In one test, diabetics who ate 1/4 teaspoon of cinnamon twice a day for 40 days reduced their fasting blood sugar 18% to 29%, triglycerides 23% to 30% and cholesterol 12% to 26%. Sprinkle cinnamon on foods such as cereal or fruit, or take it in capsules, Anderson says.

Alpha-lipoic acid. This potent antioxidant can improve blood sugar and help prevent and treat diabetic complications such as cataracts and neuropathy, says Lester Packer, Ph.D., of the University of Southern California. In German research, 600 milligrams daily significantly increased insulin sensitivity and lowered blood sugar in type 2 diabetics after four weeks.

Salacia oblonga. This herb, used in India to treat diabetes and sold on the Internet, lowered insulin 29% and blood glucose 23% in healthy adults, reports Steve Hertzler, Ph.D., of Ohio State University. But don't try it without telling your doctor, he says. Effective daily doses range from 100mg to 1,000mg, with gastrointestinal distress occurring at higher levels.