Why is diabetes an imperfect science? The last 22 years of my life with diabetes have disproved as much (or more) than it has confirmed in conventional diabetes wisdom. The facts were in the studies - but researchers didn't know what to do with them, at the time. Here's where the mysteries will unfold..

The last year blogging with The Diabetes Blog has been an in your face demonstration of the imperfect science of diabetes. Many undisclosed details of studies from days gone by have proven to be a reason why diabetes has been an imperfect science. Since when has science been imperfect? When you don't complete your homework. Don't get wrong - science has done the homework, but you - the diabetic - have not been privy to every fact found in these studies. Nowadays, there's no excuse. The dog doesn't eat my homework.

It's time these facts made it to the light of day. I am taking my investigative curiosity and hanging a shingle over LoveDiabetes.com - because that's who I am: Allison Love Beatty! Let's buddy-up with the researchers and their homework. It's about time we solved the universal mysteries of diabetes. The facts are available. With combined knowledge, existential and pathological, we can make more of these studies from yesteryear and the days to come.

Someday soon we will see the trend of diabetes reverse - less diagnosis, less complications, and reduced costs. I've got Internet access, unlimited long-distance, and plenty of time. The fun is just getting started! This is my invitation to you - what's your diabetes mystery? Leave me a comment on LoveDiabetes.com so I know what's on your mind. Together we will prove there is no such a thing as an imperfect science.

Love always,
Allie B

A type 1 diabetic mystery is why do some Type 1s get complications and others seem to never get them? A massive Japanese study of Type 1 diabetics found that those with fulminant diabetes developed complications much faster and more severely than those with non-fulminant diabetes.

The difference between fulminant and non-fulminant is the speed and intensity at which the disease develops. Fulminant Type 1 diabetes typically develops suddenly with near total loss of beta cell function. This type of diabetes is confirmed with testing c-peptide levels. Non-fulminant type 1 diabetes has residual c-peptide levels that eventually taper to undetectable. Sometimes this is seen through many years of the Honeymoon Period.

This study may be the antithesis of conventional wisdom for preventing complications. Staking all hopes on blood sugar control is heavily optimistic. Yes controlling blood sugar does lessen the workload for existing beta cells, and thus extends the lifespan of each beta cell. Research suggests that c-peptide offers protection to beta cells, both from apoptosis (cell death) and encourages new cell growth. This new cell growth applies to beta cells and other cells of the body that endure long-term Type 1 diabetes complications.

Diabetics are instructed that maintaining normal blood sugars is the Holy Grail of preventing long-term complications. Yes and no. The truth is controlling your blood sugar will not allow complications of Type 1 diabetes to develop as quickly, presuming you still had some level of beta cell function upon diagnosis (i.e., c-peptide). That doesn't sound like a reward as much as it does a delayed punishment. I'd like c-peptide with my insulin, please. It's off the à la carte menu? That's fine - serve it up! I want to thank Klausen for bringing this study to my attention.

Thomas Smith began reviewing scientific literature after conventional medicine failed him in controlling diabetes. Smith found research that shows dietary toxins impair cell membrane function. These toxins include trans fatty acids and refined sugars. Cells begin to have trouble absorbing nutrients, and the blood sugar rises. Over time, this results in chronic elevated blood and urine sugar levels. Sounds like a growing epidemic, doesn't it?

This damage to cell membranes, caused by a poor diet, can be repaired. The diabetic syndrome can be cured by eliminating all processed fats and oils. The protocol calls for supplementing high-dose Omega-3 fatty acids. This protocol normalizes blood sugars because the body is continuously repairing cell membranes by using the fats and oils available in the diet. One caution: the speed of recovery is related to the length of the illness. Some Type 2 diabetics may require up to one year for dramatic reductions in blood sugar.

A gaping hole exists between conventional medicine and diet. Conventional medicine claims that the cause of Type 2 diabetes is unknown. Medical doctors, as practitioners of conventional medicine, are not trained to explain how it happened. They treat symptoms with medicine. The business of medicine is medicine. The business of diabetes would be devasted if the cure was as simple as diet. The explanation Thomas Smith provides in his empirical studies is fascinating and I encourage anybody with competing or supporting evidence to open the debate.

Ed Hinerman, a life insurance specialist with the Hinerman Group, was posed an interesting challenge recently. For years he has successfully found affordable life insurance for many adults with type 1 diabetes, but he had never been asked about life insurance for children with Type 1 diabetes until now.

After speaking with underwriters in the top 40 or so companies, he found a discernible lack of interest due to lack of data. Companies would say that they couldn't consider someone with type 1 diabetes until they were either age 15 or age 20. A peer in the industry told Ed the knee jerk reaction was because insurance companies haven't done mortality studies on children. They simply don't have any data upon which to base the pricing for products. Uh oh!! That coupled with the fact that there really isn't any financial incentive for them to study and create products for a relatively small market that would produce relatively low premium, kind of sets the tone. Well, now the war has been defined and the battles are becoming clearer.

When Ed contacted the ADA for assistance in this matter - hold your breath (it's a shocker!) - they turned a cold shoulder on a diabetic's need. What if the diabetic's parents were doing what so many families do - and trying to buy a whole life policy to help pay for their kids college someday? It's really not fair! Here's where fair begins -- Ed asked me to gather some facts it will take to get the insurance companies attention. Does anybody have any idea of the mortality rate of children after being diagnosed with type 1 diabetes?

Bottom line. Life insurance companies make big money and for them to cut and run from children just because it might not make them more big bucks, or because they really haven't done their homework and aren't interested in doing it, isn't acceptable. Game on! I hope we can make a good showing, at the very least - hit one out of the park for the fans. Thanks for inviting me to play, Ed!

Dr. Bernstein, a world leading authority in diabetes, is hosting a live internet broadcasts to answer your questions on diabetes. Diabetes 911 is setup to stop the complications of diabetes before it's an emergency. Here's a link to the page where you can submit your questions, to be answered on his next broadcast -- September 19, 2007.

Just a heads-up for The Diabetes Blog reading community - AOL has announced they will be retiring The Diabetes Blog on September 14, 2007. So this is a preemptive blog to get your calendar out, send yourself a reminder email titled: OPEN ON SEPTEMBER 19th!!!!

This will not be my last blog shared with you, all mighty readers of the blogosphere. I'm working to get my proverbial welcome mat in place to continue unfolding the mysteries of diabetes on LoveDiabetes.com. More to come...

My recent blog on interlopers offering advice about controlling diabetes upset a good friend of mine. He asked a question that gave me one of those What if...dream sequences. The reality check warrants a new blog.

He asked -- what if an interloper talked your doctor into reconsidering the use of natural animal insulins because they read the research and figured out that it was the better choice? Would you still think interlopers have no value in diabetes control?

Touché` - you sunk my battleship. I had to confer with a fellow diabetes OC blogger to get the he said / she said feedback. She made a very good point, too. In her words, there is a special group of non-diabetics who have an acute understanding of the disease, and who may have a somewhat intuitive understanding of how it works, but most of the time there is a silent acknowledgement that their opinion can at any given time be dismissed in favor of the diabetics'. Words of wisdom typed from the sorceress of Lemonade Life.

Today's lesson for Allie: listen without prejudice. Learn from all who are willing to share their experiences. Prosperity in life comes from the gifts we share with each other. My friends have shared valuable insight to teach me how to gain from every experience in life. I now see that the advice others have to share is the gift we have yet to receive. Denying the gift before we ever receive it is ungrateful. Graciously humbled - Allie B

UCLA researchers report Nevada County, California residents have the lowest rate of diabetes in the state -- 2.6 percent. That's about one-third the state-wide average (6.8 percent), and slightly less than one-quarter the prevalence of diabetes in Imperial County (11.2 percent).

Take a few guesses why Nevada County's rate of diabetes is so much lower than Imperial County, and well under the national average of 7 percent. Do families eat less processed food around the dinner table? More jogging trails? Better health insurance coverage? Researcher Theresa Hastert states, "There is no one thing, but higher income is associated with better foods and exercise."

Hastert explained Nevada County is mostly white, affluent, educated and insured. Imperial County has a large population of Latinos and migrant farm workers. Nevada County's numbers support general findings that minorities without affordable, continuous health care are more prone to the disease. Who's got time for the dinner table -- Hastert openly speculates eating more junk food may be a consequence of dodging between three jobs just to get by. Also, Nevada County is a beautiful area -- she wonders if environmental factors play a role.

Is diabetes a socio-economic disease? If so, we're in trouble. The gap is widening between our nation's haves and have nots, and large concentrations of poor minorities may explain the disproportionate rates of diabetes from county to county. Read more in The Union.

Ok, sounds like a joke - but seriously, TuDiabetes is growing like gangbusters! Meredith Cummings wrote a great article on TuDiabetes and its explosive growth! The online community for people touched by diabetes, is growing at a rate of 10% per week. Way to go, Manny!

And why shouldn't we all plant a flag in this real estate? TuDiabetes offers nonstop support through conversations, debates, mysteries and revelations - all amounting to some degree of resolve. TuDiabetes is a great place to remind you that we're not alone in this dark tunnel. Need some light? Ask and you shall receive. And, by the way - you can get the answer to the lightbulb question by signing in and friending Meredith Cummings.

I logged in today and saw a great question. A member named Cody asks if others are annoyed when people who don't know what it's like to be diabetic try to offer advice. The group of interlopers is frankly growing like a virus. I define the interlopers as people who feel they know the world of diabetes without having landed on the tarmac! It's easy to study the playbook. It's a whole different ballgame to get your butt on the field. Good luck with college, Cody!

A recent study found that 87% of patients who experienced an adverse symptom from a prescribed drug spoke to their doctor. However less than half of the doctors went through with filing the adverse event paperwork to notify the drug manufacturer. Why is this?

The research was published in the latest issue of Drug Safety. Doctors dismissed patients' complaints, and told them their symptoms were not connected to use of the drug. One doctor commented that the time it takes to complete the adverse event drug paperwork is time-consuming, and often not worth it unless it is life threatening. Would Hippocrates have accepted that answer? Please review your Hippocratic Oath, doc.

Your doctor is too busy to file the necessary paperwork to notify the FDA a drug is potentially harmful. What is a patient to do? Good question and here's an answer! If you experienced any adverse side effects from the use of a prescription drug, please let the FDA know. Click BEGIN and bring this monkey business to an end!

In two weeks, Bernard Farrell will be riding in the Bike the Miles annual fundraiser to support Dr. Faustman's research to cure Type 1 diabetes. His participation is especially intrinsic because it is one day away from his 35th anniversary of becoming a Type 1 diabetic.

Bernard plans to raise $10,000 for Dr. Faustman's research. Last year he raised $7,500. The entire event raised a whopping $301,000! All of this funding is going toward the human trials to cure Type 1 diabetes. After discovering that the insulin-producing islet cells of the pancreas are capable of regeneration, Dr. Faustman now needs to test her treatment, already known to be safe in humans, to see if the effects are as positive as they were in the animal model.

It goes without say that this is terribly important for Bernard as much as it is for every man, woman and child touched by Type 1 diabetes. Bike the Miles is an annual event that was started by Susan Root and Jacqueline Fusco in 2004. Both, Susan and Jacqueline, have children who are Type 1 diabetics. Please visit Bernard's site to support his ride and the drive to cure Type 1 diabetes!

Jennifer Ordoñez, a Newsweek journalist who is also a Type 1 diabetic, reported on her experience at a triathlon training camp geared for diabetics. After reading her report, I was curious as to why hypoglycemia would cause a diabetic to fail the VO2 max test.

Nobody likes failing tests - especially when it comes to something as important as VO2 max. VO2 max is the maximum amount of oxygen a person uses while exercising at their limit for one minute. If you are in shape, your muscles will use a lot of oxygen to create energy. The prime source of energy for the body comes from blood sugar. When Jennifer took her VO2 test her blood sugar was falling and she failed. Apparently when blood sugar is falling the body puts itself into energy lockdown which compromises even conditioned athletes VO2 max.

Hypoglycemia causes muscles to fatigue quicker. Muscle fatigue is the result of inadequate oxygen availability. Prevention of hypoglycemia is one of the major objectives of adequate blood sugar when you are about to work out. By maintaining optimal blood sugar, you can assure a better level of exercise performance. I know better than to tell you what to do. But as a friendly reminder: make sure you've fueled up adequately before you hit the gym or the open road to work on your VO2 max.

I'm outraged at the coverage CNN provided on diabulemia. They accuse diabetics who suffer with the condition of doing the wrong thing. CNN neglected to address the cause of diabulemia. The drug all insulin dependent diabetics must use is a synthetic hormone that has been genetically modified. It is nothing like human insulin or any natural vertebrate insulin, for that matter.

Make it right, CNN. Mass media should be the defenders of righteousness, not the accomplices to Big Pharma. Do a study comparing human insulin (natural vertebrate insulin) and genetically modified insulin. The comparison should include: penetration zones of the body, hormonal reactions stimulating and suppressing hunger, amino acids, c-peptide, lipophilic and hydrophilic nature, and pH values. The difference in natural human insulin and Lantus pH is remarkable: 7.5 to 4.0. How similar is that? CNN you've slipped on the peel and missed the facts. Now perform your due diligence to help make it right. I ask every insulin dependent diabetic to email CNN and ask them to put the facts on the line. Link to this blog so they have an idea of where to start. Thank you!

A new study by Kaiser Permanente's Center for Health Research carries both good news and bad news. Bad news first -- research of 9,439 mother-child pairs shows maternal blood sugar is tied to a future risk of obesity in offpsring. Pregnant women with above-normal blood sugar levels were twice as likely to have overweight kids. Across all racial and ethnic groups, the higher the mother's blood sugar during pregnancy, the greater the chance her offspring would develop obesity by 5 to 7 years of age.

Now if you're pregnant and you've been diagnosed with high blood sugar, take a deep breath. The good news is the risk of childhood obesity is reversible if elevated sugars are treated through diet, exercise and insulin (if required). At particular risk are women with sugar levels higher than normal, but not high enough to be deemed gestational diabetes. They were more likely to have obese children than women treated for gestational diabetes or those with normal sugars.

Borderline blood sugars are nothing to ignore. I shared in a previous post that moderately elevated glucose during pregnancy is associated with other problems such as cesarean section and heavier babies. Gestational diabetes criteria may widen. Also, Deanna reported earlier this month that gestational diabetes is linked to pancreatic cancer.

Recently I posted on the California Department of Education's recent lawsuit settlement with the American Diabetes Association. CDE promised students would have access to legally-required diabetes care on campus. With a shortage of school nurses, CDE agreed caregivers could include trained volunteers. I came away from the agreement thinking, "Good! It may have taken a lawsuit, but problem solved." But this settlement is hardly a neatly wrapped package.

Liability drives many decisions. Now the California School Nurses Organization has advised school nurses to seek guidance from district lawyers before training volunteers. Nurses are concerned they could lose their licenses if they train non-medical staff. Executive Director Nancy Spradling stated insulin injections should be monitored by licensed personnel -- incorrect calculations can be fatal or trigger a coma. They've got a point.

Student diabetes care varies widely in California. With a student population of 22,000, Lake Elsinore Unified School District is doing a good job. They have eight nurses taking care of 70 students with diabetes. Last year, Palm Springs Unified School District had only 3 nurses for 24,000 students, requiring parents to visit district schools daily to inject children too young to handle the task themselves.

Arlene Mayerson, directing attorney with the Disability Rights Education and Defense Fund (they represented the ADA in the lawsuit), stated California has one of the lowest nurse-to-student ratios. Perhaps a new certification for a 'School Diabetes Specialist' is on the horizon. Regardless, I hope the CDE figures out a solution to honor the settlement. I bet school districts across the country are watching -- the health of students with diabetes is at stake. Don't forget the nurses' concern. Beyond losing their licenses, no one wants to see a student with diabetes hurt or killed due to an improperly trained, unlicensed adult volunteer. Read the full story in The Press Enterprise.

Bev did a great job covering the study of obese mice having protection from elevated blood sugar due to a plethora of adiponectin. Adiponectin was shown to enhance insulin signaling which transported the excess glucose to less harmful areas of the body, rather than the cells which would endure diabetes complications. The results of this study created a condition called ratones mórbidamente obesos - which sounds better in Spanish because in English this means morbidly obese mice.

You know what they say about hindsight, right? A study from a year ago revealed some good news and some bad news. Good news first - turns out Type 2 diabetes drugs using troglitazone increased adiponectin. Rezulin was one of these drugs, but it was removed from the US market March 21, 2000. Now the bad news, the Type 2 diabetes drugs made with metformin were shown to reduce adiponectin. A few of the drugs that use metformin are Fortamet, Glucophage, Glucophage XR, and Riomet.

So why must diabetics be led with imperfect vision? Because the bottom line is researchers and doctors believe they are saving lives every day. Yes, they do. But there is a lot to behold when you tinker with His design. Remember the movie Malice? These lines don't make it into movies for nothing. Producers know human nature and they stretch it to the extreme. Whether or not you want to admit it - you know a few people with a complex like Alec Baldwins. Alec Baldwin says, "You ask me if I have a God complex. Let me tell you something: I am God". Click for the entire 1:30 scene, courtesy of YouTube.

You've probably heard it in the news lately. The number of overweight children and teenagers aged 6-19 has nearly tripled over the last 40 years. Type 2 diabetes is not an adult-only disease anymore, adolescents are developing it. If we don't turn this trend around, many kids will have heart trouble by the age of 30 or 40. Healthier school fare is a part of the solution, but I believe parental influence on meal and snacking habits is most crucial. As your children head off to school in the coming days, do not forget about packing a healthy school snack (if required) ... I'll write later on healthy school lunches.

My little guy will step on the bus today for his first day of kindergarten. He is thrilled. He is ready. We walked the school hallways during an orientation earlier this week, and yesterday we had a kindergarten briefing where we learned all about school policies. The policy-chat was briefly interrupted by a tornado warning, where the entire school hit the deck in the hallways for 20 minutes, but luckily, no twisters!

As the policy-talk ensued, the teacher announced daily snacks must be healthy. Juice boxes were not allowed. A water bottle was fine, but the drinking fountain even better. Geez, I was starting to really like this school. Fruit and vegetables were strongly suggested, but no cookies, mile-high frosted cupcakes or sugary fruit snacks. I nearly stood up and clapped, but I didn't want to freak out a roomful of mommy strangers. After reading Allie's recent post on water, I will definitely pack a water bottle.

Yesterday afternoon we headed to the store and Frank picked out his snack -- he searched and searched until he found a perfectly shaped green apple. It's in his backpack, ready and waiting for his first day of big kid school. If you're shopping for school snacks, here is a helpful list of ideas to bring. Think fruits and vegetables. Don't throw those sugary graham crackers in your shopping cart. Stay away from the processed carbohydrates. This is your chance to develop healthier habits for a lifetime. Hey, you might not even need to be the fall guy -- hopefully it's "school policy."

It's free, it covers 70% of the Earth's surface, and it's a remedy for all living things. So why do physicians rarely promote the curative properties of water?

Every plant needs it to survive. Every living thing on Earth requires water - even the cacti of the Sahara Desert. We are no different. Mike Adams, of News Target, was one of the last people to interview the late Dr. Batmanghelidj. The things he learned about "The Healing Power of Water" left him in awe. The conversation revealed which ailments and "diseases" are actually caused by dehydration, why the general population is chronically dehydrated and henceforth labeled diseased, what ingredients deplete the body's water reserves, why thirst is not a reliable indicator of dehydration, the dynamics of cholesterol and how water keeps it in balance, how dehydration impairs mental functioning and potentially causes depression, in addition to recognizing signs that your body is starting to dehydrate.

It's a world of answers to an often overlooked question. The premise of the interview is this one thing: the human body manifests dehydration by producing pain, and pain is a sign of water shortage in the body, and water shortage is actually the background to most of the health problems in our society. If the aforementioned interests you in the least - I strongly encourage you to follow the river of curiosity to its source. Who knows? Maybe we're all dying of thirst.

Previous studies have examined visual impairments of Caucasians with type 1 diabetes, but this is the first study analyzing vision loss for African Americans with type 1.

The vision and associated risk factors of approximately 500 African Americans with type 1 were studied over a 6-year period. At follow-up, 4.3 percent of patients realized vision loss in their better eye (visual acuity of 20/40 or worse) and 0.6 percent became blind in their better eye (visual acuity of 20/200 or worse). Nearly 10 percent lost 15 or more letters on the eye chart due to a doubling of the visual angle in their better eye. Another 13.5 percent had this doubling in either eye, which the researchers stated was "particularly high".

Independent predictors of vision loss over the six years were identified as poor blood sugar control, older age, high protein levels in the urine (symptomatic of kidney disease) and diabetic retinopathy, a common degeneration of the retina seen in people with diabetes.

Dr. Monique S. Roy, of the University of Medicine and Dentistry of New Jersey in Newark, stated African Americans with diabetes as a whole have poor blood sugar control. Beyond efforts to improve glucose control, monitoring retinopathy in this population can identify those requiring treatments to prevent severe vision loss. The study is published in the Archives of Ophthamology.

This story in Reuters does not mention why African Americans with type 1 might have poorer control leading to vision problems. One factor is likely a lack of health insurance. I did a little digging. According to the Commonwealth Fund Biennial Health Insurance Survey, 33 percent of working age African American adults were medically uninsured or experienced a gap in insurance in 2005. The numbers are even worse for Hispanics. Most troubling, African Americans have higher rates of health problems among lower and higher income groups compared to both Caucasians and Hispanics.