I don't mind high sugars as much as I loathe lows. Personally I'm not so ruffled by shots either (but my liver begs to differ). However, in a message posted on The Islet Foundation, Pfizer reported that insulin-dependent diabetics declared they most hate taking shots. Was this the warm-up for the Exubera campaign? Here's a fact I support! A close second to this hatred is the hypos. Any diabetic will confess -- hypos are unforgiving. So what if you could catch two birds with one capsule?

I must reiterate the scientific genius behind the Oramed gel caps. The encapsulated insulin bypasses destruction in the stomach cavity. It reaches an entry point in the intestines where it reports for duty to the liver. This allows the liver to resume command of the glucose metabolism, just like Mother Nature intended. Whey you inject insulin - you are overriding the livers ability to monitor blood sugar and putting yourself in the line of fire for the dangerous lows. We all know this state of derangement too well. You won't find my lows picture on a milk carton if I happen to lose it, either.

Frequent episodes of hypoglycemia (even mild ones) force the brain to become accustomed to the low glucose. Unfortunately this also causes suppressed signaling of adrenaline, the livers last resort before dangerous lows. More specifically, the glucose transporters located in the brain cells are damaged from frequent episodes of hypoglycemia. So what was once the hypo threshold for the brain to signal adrenalin release becomes lower. Clinically, the result is hypoglycemic unawareness. Down with the shots, down with the lows and big ups with the future of diabetes control! Now we're getting somewhere.

How did we allow insulin to evolve into a genetically modified hormone?

It all boils down to propaganda. If you're confident your current insulin surpasses former natural insulin in: purity, availability, allergy response, similarity and safety - I encourage you to review the following facts that were conveniently neglected or not available, due to restraints of time travel.

Purity: In the 1970s, a Genentech scientist stated that natural insulin was incredibly pure. In the 1980s, rDNA humulin insulins were less pure than the natural insulins of the 70s. The advertising campaign for rDNA insulin suggested otherwise. Here's a quote, as printed in the book, Invisible Frontiers: "They impressed upon us very, very clearly that this (human insulin) was going to be no advantage at all."

Supply and demand: A USDA scientist told the world the diabetic population's insulin needs would outstrip the supply of natural pancreatic glands. This was sensational propaganda. Have you visited McDonald's or Wendy's lately? There doesn't seem to be a shortage of Big Mac's, does there?

Allergy response: About 5-10% of the diabetic population is allergic to natural analog insulins. Today, based on 25 years of human diabetic experimentation, the diabetic population is showing the same 5-10% allergic response to all the new products. Maybe that aforementioned 5-10% is the same latter 5-10%? From the looks of it - they're just allergic to insulin, rDNA, GM or natural.

Similarity to own insulin: rDNA human insulin is just like the body makes. Who wouldn't want to take human insulin? That's the propaganda. A recent research article found in a large portion of the diabetic population, their own human insulin may actually be the cause of their diabetes. Something tells me the study included the same 5-10% of diabetics mentioned in the allergy response paragraph.

Safety: Drug companies touted rDNA insulins as providing a good a warning to diabetic patients as natural analog insulins regarding low blood glucose levels. Are you kidding me? Driver and workplace accident statistics regarding diabetics indicate that the rDNA insulins do not cross the blood-brain barrier in the same manner as natural analog insulins. The part of the brain controlling endocrine response lags because it doesn't get the signal until it's too late (if it ever gets the message). The increase of diabetes-realted deaths since the introduction of rDNA insulin is remarkable! (Center for Disease Control). How safe is that?

Fact versus fiction is a scary line to smear for the sake of business. I suggest doctors, diabetes educators, and patients review the facts today and compare it to the propaganda in the 80s. There is no suppressing the truth!

In the fall of 1985, a very scary thing happened shortly after I was diagnosed with type 1 diabetes. One morning I woke up and I couldn't remember things I would normally remember. I couldn't remember the name of my neighbor's dog. I had a fanatical love for Cookie. Of course I would remember Cookie! A diabetic child would never forget such a sweet name for such an adorable dog! One more thing -- I had a pounding headache.

My mom brought me to the hospital, where my endocrinologist met us. They ran test after test and nary could an expert explain my memory loss. They confirmed I was experiencing amnesia, which turned out to be temporary because I was back to normal the next day.

How many people have experienced this same phenomenon? I surmised that this was my body reacting to the Humulin insulin I had started only a month or so before. The insulin must have been competing with my body's own attempts to generate insulin thus thwarting my blood sugar down into a dangerous hypoglycemic state. A study published in 1991 shows that hypoglycemia results in a lesion in the left temporal lobe. I have one of those lesions now, but it wasn't discovered until 2000. Oh yeah - and my peduncle is perfectly asymmetric. What does that mean anyway?

Why weren't doctors informed of this potential reaction to insulin in 1985? A study 6 years later is a few years too late. And how many more newly diagnosed insulin-dependent diabetics experience the same thing? My parents were scared out of their mind and nobody (including specialists) had any idea what to do with me.

I contacted Novo Nordisk back in March to tell them about the remarkable effects C-peptide had on reversing complications of Type 1 diabetes. I asked if they would bring the drug to market. A mass of excitement overwhelmed me when I learned about C-peptide missing from insulin all these years. The response from Novo? No thanks, it's not one of our targets. Targets, eh?

C-peptide is a byproduct of the production of insulin. In Type 1 diabetics, the level of C-peptide eventually becomes undetectable due to the body not making any insulin of its own. Long-term complications of diabetes frequently develop despite insulin therapy and optimal blood glucose control. C-peptide could quite possibly be the missing link in perfect diabetes control. I sent the following document to Novo Nordisk and asked them to make C-peptide available to reverse and ameliorate renal and nerve dysfunction for Type 1 diabetics. Read the document and see for yourself the eye-popping beneficial results C-peptide offers Type 1 diabetics. I received it directly from Dr. Wahren, lead researcher for C-peptide.

After 5 months consideration, Novo called me back. They said C-peptide is not a target for their company. I understand and now Levemir is not a target in my diabetes control, either. For all the Type 1 diabetics out there controlling your sugars with insulin not really made with you in mind -- do you understand why Novo does not wish to develop this critically important treatment? I guess insulin is good enough, right? Wrong. It's a tough job but somebody's got to do it. Just not Novo. When you are in the business of diabusiness -- no thank you says so much about what could potentially hurt your business.

Last November, I forgot to take my Swiss Army Champ Knife out of my purse before going to JFK Airport. So, for being stupid, it cost me a kick-ass pocket knife I'd had since 6th grade. Live and learn. But this is pretty interesting - turns out a fellow blogger over at Gadling had an airport security faux pas, as well. Dare I suggest another forgetful diabetic was the culprit permitting the breach of security?

Jamie Rhein's husband was chosen for a routine safety inspection before the family boarded the Skybus. His carry-on was inspected. The goods included: liquid hand-cleaner, a pair of scissors and a mini-wine tasting kit. The kit, unopened at the time - was opened and the corkscrew was confiscated by security. There was a knife attached. The pair of full-metal scissors was allowed. The liquid gel wasn't given back. Red alert danger - I know how tricky soap can be. Watch out!

The irony of Jamie's experience is that halfway through the flight she found an unused hypodermic needle and syringe still in the packaging and two empty medicine vials under her 5 year-old son's seat. One of the crew said there had been a diabetic on board the previous flight. Good cleanup crews are hard to find. That's fine, but with all that security, it was an awakening to be on the lookout for a used needle when searching for her son's spilled crayons. Guess there's no avoiding being on incessant heightened alert. Speaking of -- I asked JFK security to donate my Swiss Army knife, after they told me I had to surrender it. Yeah right. I'm sure the dude who patted me down took it home. Keep it sharp, buddy!

The renowned author of The Diabetes Solution, Dr. Richard Bernstein is now ready and waiting to answer your questions on The Bernstein Connection.

In 1946, at the age of 12, Richard Bernstein developed Type 1 Diabetes, and for more than two decades, he was what he calls, "an ordinary diabetic"-one who dutifully followed doctor's orders. Despite his diligence with maintaining the disease, the complications from his diabetes worsened over the years, and like many diabetics in similar circumstances, he faced death at a very early age. Though he was indeed still alive, the quality of his life wasn't good, and by the time he reached his twenties and thirties, many of his body's systems began to deteriorate. Now, beyond his best selling books, Dr. Bernstein is opening up the airwaves to those who wish to learn from his real world experiences and conquer the daily hurdles of diabetes. He's doing so through The Bernstein Solution, offering direct access to Dr. Bernstein's methods, latest advice on diabetes, best selling books, and regular live broadcasts where Dr. Bernstein answers your questions.

I was fortunate enough to listen to his last broadcast, from August 8th. I do own The Diabetes Solution but I'm strongly considering joining The Bernstein Connection. The broadcast I listened to was as informative, if not more so, than the book! For $80 a year - if it can help a diabetic reverse damage to their eyes and kidneys, I don't think it's unreasonable at all!

Irreverence. Curiosity. A fighting spirit. Surprising information. We've got all this and more over at our sister sites covering cancer and cardio issues. To find out why we should all "puck cancer" or invest in a heart rate monitor (not to mention drink our afternoon tea), read on ...

The Cardio Blog
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Light cigarettes are just as dangerous for the heart
Think you're too young and healthy for a heart attack? Think again!
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Reduce stress one cup of tea at a time

The Cancer Blog
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