Why is diabetes an imperfect science? The last 22 years of my life with diabetes have disproved as much (or more) than it has confirmed in conventional diabetes wisdom. The facts were in the studies - but researchers didn't know what to do with them, at the time. Here's where the mysteries will unfold..

The last year blogging with The Diabetes Blog has been an in your face demonstration of the imperfect science of diabetes. Many undisclosed details of studies from days gone by have proven to be a reason why diabetes has been an imperfect science. Since when has science been imperfect? When you don't complete your homework. Don't get wrong - science has done the homework, but you - the diabetic - have not been privy to every fact found in these studies. Nowadays, there's no excuse. The dog doesn't eat my homework.

It's time these facts made it to the light of day. I am taking my investigative curiosity and hanging a shingle over LoveDiabetes.com - because that's who I am: Allison Love Beatty! Let's buddy-up with the researchers and their homework. It's about time we solved the universal mysteries of diabetes. The facts are available. With combined knowledge, existential and pathological, we can make more of these studies from yesteryear and the days to come.

Someday soon we will see the trend of diabetes reverse - less diagnosis, less complications, and reduced costs. I've got Internet access, unlimited long-distance, and plenty of time. The fun is just getting started! This is my invitation to you - what's your diabetes mystery? Leave me a comment on LoveDiabetes.com so I know what's on your mind. Together we will prove there is no such a thing as an imperfect science.

Love always,
Allie B

Insulin not only moves glucose into the cells, but it also escorts Vitamin C. Blood sugar hogs the seats on the bus in most diabetics, therefore reducing the amount of Vitamin C we can absorb. This is the premise of The GAA Theory: high glucose levels hinder vitamin C entry into cells.

Vitamin C is vitally important for many functions throughout the body - a big one being metabolism. Glucose and Vitamin C are similar in the way they enter the cells. Both molecules require help from insulin. The name for the process that brings glucose and Vitamin C through cell membranes is insulin-mediated uptake. The insulin-mediated uptake of glucose and vitamin C uses white blood cells. White blood cells have more insulin pumps and they may contain 20 times the amount of vitamin C as ordinary cells.

So does increasing your Vitamin C help boost your glycemic control? Diabetes Health cited a study that confirms daily doses of 2,000 mg of absorbic acid improved both fasting blood glucose and HbA1c readings in patients with type 2 diabetes. Next time you swing by the store - see if some Emergen-C can help you achieve better glycemic control. With 1,000 mg of Vitamin C per packet - their homepage says: Feel The Good. Little did they know how good it could be for Type 2 diabetics!

Thomas Smith began reviewing scientific literature after conventional medicine failed him in controlling diabetes. Smith found research that shows dietary toxins impair cell membrane function. These toxins include trans fatty acids and refined sugars. Cells begin to have trouble absorbing nutrients, and the blood sugar rises. Over time, this results in chronic elevated blood and urine sugar levels. Sounds like a growing epidemic, doesn't it?

This damage to cell membranes, caused by a poor diet, can be repaired. The diabetic syndrome can be cured by eliminating all processed fats and oils. The protocol calls for supplementing high-dose Omega-3 fatty acids. This protocol normalizes blood sugars because the body is continuously repairing cell membranes by using the fats and oils available in the diet. One caution: the speed of recovery is related to the length of the illness. Some Type 2 diabetics may require up to one year for dramatic reductions in blood sugar.

A gaping hole exists between conventional medicine and diet. Conventional medicine claims that the cause of Type 2 diabetes is unknown. Medical doctors, as practitioners of conventional medicine, are not trained to explain how it happened. They treat symptoms with medicine. The business of medicine is medicine. The business of diabetes would be devasted if the cure was as simple as diet. The explanation Thomas Smith provides in his empirical studies is fascinating and I encourage anybody with competing or supporting evidence to open the debate.

Dr. Bernstein, a world leading authority in diabetes, is hosting a live internet broadcasts to answer your questions on diabetes. Diabetes 911 is setup to stop the complications of diabetes before it's an emergency. Here's a link to the page where you can submit your questions, to be answered on his next broadcast -- September 19, 2007.

Just a heads-up for The Diabetes Blog reading community - AOL has announced they will be retiring The Diabetes Blog on September 14, 2007. So this is a preemptive blog to get your calendar out, send yourself a reminder email titled: OPEN ON SEPTEMBER 19th!!!!

This will not be my last blog shared with you, all mighty readers of the blogosphere. I'm working to get my proverbial welcome mat in place to continue unfolding the mysteries of diabetes on LoveDiabetes.com. More to come...

My recent blog on interlopers offering advice about controlling diabetes upset a good friend of mine. He asked a question that gave me one of those What if...dream sequences. The reality check warrants a new blog.

He asked -- what if an interloper talked your doctor into reconsidering the use of natural animal insulins because they read the research and figured out that it was the better choice? Would you still think interlopers have no value in diabetes control?

Touché` - you sunk my battleship. I had to confer with a fellow diabetes OC blogger to get the he said / she said feedback. She made a very good point, too. In her words, there is a special group of non-diabetics who have an acute understanding of the disease, and who may have a somewhat intuitive understanding of how it works, but most of the time there is a silent acknowledgement that their opinion can at any given time be dismissed in favor of the diabetics'. Words of wisdom typed from the sorceress of Lemonade Life.

Today's lesson for Allie: listen without prejudice. Learn from all who are willing to share their experiences. Prosperity in life comes from the gifts we share with each other. My friends have shared valuable insight to teach me how to gain from every experience in life. I now see that the advice others have to share is the gift we have yet to receive. Denying the gift before we ever receive it is ungrateful. Graciously humbled - Allie B

UCLA researchers report Nevada County, California residents have the lowest rate of diabetes in the state -- 2.6 percent. That's about one-third the state-wide average (6.8 percent), and slightly less than one-quarter the prevalence of diabetes in Imperial County (11.2 percent).

Take a few guesses why Nevada County's rate of diabetes is so much lower than Imperial County, and well under the national average of 7 percent. Do families eat less processed food around the dinner table? More jogging trails? Better health insurance coverage? Researcher Theresa Hastert states, "There is no one thing, but higher income is associated with better foods and exercise."

Hastert explained Nevada County is mostly white, affluent, educated and insured. Imperial County has a large population of Latinos and migrant farm workers. Nevada County's numbers support general findings that minorities without affordable, continuous health care are more prone to the disease. Who's got time for the dinner table -- Hastert openly speculates eating more junk food may be a consequence of dodging between three jobs just to get by. Also, Nevada County is a beautiful area -- she wonders if environmental factors play a role.

Is diabetes a socio-economic disease? If so, we're in trouble. The gap is widening between our nation's haves and have nots, and large concentrations of poor minorities may explain the disproportionate rates of diabetes from county to county. Read more in The Union.

Ok, sounds like a joke - but seriously, TuDiabetes is growing like gangbusters! Meredith Cummings wrote a great article on TuDiabetes and its explosive growth! The online community for people touched by diabetes, is growing at a rate of 10% per week. Way to go, Manny!

And why shouldn't we all plant a flag in this real estate? TuDiabetes offers nonstop support through conversations, debates, mysteries and revelations - all amounting to some degree of resolve. TuDiabetes is a great place to remind you that we're not alone in this dark tunnel. Need some light? Ask and you shall receive. And, by the way - you can get the answer to the lightbulb question by signing in and friending Meredith Cummings.

I logged in today and saw a great question. A member named Cody asks if others are annoyed when people who don't know what it's like to be diabetic try to offer advice. The group of interlopers is frankly growing like a virus. I define the interlopers as people who feel they know the world of diabetes without having landed on the tarmac! It's easy to study the playbook. It's a whole different ballgame to get your butt on the field. Good luck with college, Cody!

A friend of mine told me about a friend of hers who had a cat that used to have diabetes - until she left him with the Vet. Her friend was overprotective of her little cat since it was diagnosed with diabetes. The cat was put on insulin injections. She also upgraded the entire posse of cats to low-carb cat food. Routinely she took her cat to the vet to have the blood sugar levels checked ($75 a pop!) So far, so good - the story is mundane until her friend left for a vacation and boarded the cat at the Vet's for the week.

All week her friend was worried about the welfare of her cat - even though she was safely under the watchful eye of the vet. As it turns out, upon her return from vacation - the vet notified her that her cat no longer has diabetes. She was sent home with instructions to continue feeding the cats low carbohydrate food, and to discontinue the insulin injections.

Cornell University College of Veterinary Medicine says, "Some diabetic cats may lose the need for insulin, months or years after diagnosis. If diabetes has resulted from obesity, it is likely to improve a great deal-or even completely resolve-once the cat's weight is under control. If obesity or some other disorder is not a factor, the diabetes probably will not go away; however, it can be successfully managed."

So here's my question: are animals so different from human beings? Why isn't the equation so simple in curing Type 2? Simple is a grave understatement - but understanding the cause of elevated blood sugar could be the great escape from diabetes. It's more than just switching a diet to low-carb cat food, isn't it? Meow.

Diabetic foot complications are responsible for many lower extremity amputations. But this last drastic step can be prevented up to 85 percent of the time with early diagnosis and proper care.

Now Thai researchers and physicians have shown using a patient's own stem cells can effectively heal chronic foot wounds. Diabetes patients with chronic foot wounds, aged 50-72, were injected with stem cells obtained from their own blood. Most excitedly, the wounds healed nicely within three to four months. The stem cell treatment also makes fiscal sense. According to this article, stem cell treatment for wounds in a patient with diabetes costs about $6,000, one-fifth the cost of conventional treatment for a leg wound.

Studies have shown primary care physicians often fail to examine the feet of patients with diabetes. It's a shame, as this step is the least costly and most effective way to prevent foot wounds and potential amputations. But at the same time, it is nice to know there is a promising, cheaper treatment utilizing patient-donated stem cells.

Creator of Diabetes Health Magazine, Scott King, has been a type 1 diabetic for over 34 years. Needless to say, he knows diabetes, and he is doing a remarkable job of introducing cutting-edge treatments for diabetics. In the first Diabetes Health TV broadcast, he shared interviews from the recent AADE Conference. A really exciting product he featured is called Neuragen - a topical treatment for diabetes neuropathy.

With diabetes neuropathy, people experience pain due to damage to the peripheral nerves. Neuropathic pain is often characterized by burning sensations or shooting pain, or may occur as numbness or chronic itching. Clinical trials have shown Neuragen to be effective in 70% of patients for the pain associated with diabetes. The ingredients are pretty kosher, too. Neuragen is made of a proprietary blend of essential oils from special species of geranium, lavender, bergamot, eucalyptus, and tea tree.

The Neuragen rep was blunt when he described the effective nature of this all natural product - using more does not make it any more effective! You have to admire his refreshing honesty. But like I said upfront - if Scott King is willing to spend the time getting the scoop on this product - it's probably worth your time using it. For more interviews, checkot the full coverage of the AADE Conference on Diabetes Health TV!

How did we allow insulin to evolve into a genetically modified hormone?

It all boils down to propaganda. If you're confident your current insulin surpasses former natural insulin in: purity, availability, allergy response, similarity and safety - I encourage you to review the following facts that were conveniently neglected or not available, due to restraints of time travel.

Purity: In the 1970s, a Genentech scientist stated that natural insulin was incredibly pure. In the 1980s, rDNA humulin insulins were less pure than the natural insulins of the 70s. The advertising campaign for rDNA insulin suggested otherwise. Here's a quote, as printed in the book, Invisible Frontiers: "They impressed upon us very, very clearly that this (human insulin) was going to be no advantage at all."

Supply and demand: A USDA scientist told the world the diabetic population's insulin needs would outstrip the supply of natural pancreatic glands. This was sensational propaganda. Have you visited McDonald's or Wendy's lately? There doesn't seem to be a shortage of Big Mac's, does there?

Allergy response: About 5-10% of the diabetic population is allergic to natural analog insulins. Today, based on 25 years of human diabetic experimentation, the diabetic population is showing the same 5-10% allergic response to all the new products. Maybe that aforementioned 5-10% is the same latter 5-10%? From the looks of it - they're just allergic to insulin, rDNA, GM or natural.

Similarity to own insulin: rDNA human insulin is just like the body makes. Who wouldn't want to take human insulin? That's the propaganda. A recent research article found in a large portion of the diabetic population, their own human insulin may actually be the cause of their diabetes. Something tells me the study included the same 5-10% of diabetics mentioned in the allergy response paragraph.

Safety: Drug companies touted rDNA insulins as providing a good a warning to diabetic patients as natural analog insulins regarding low blood glucose levels. Are you kidding me? Driver and workplace accident statistics regarding diabetics indicate that the rDNA insulins do not cross the blood-brain barrier in the same manner as natural analog insulins. The part of the brain controlling endocrine response lags because it doesn't get the signal until it's too late (if it ever gets the message). The increase of diabetes-realted deaths since the introduction of rDNA insulin is remarkable! (Center for Disease Control). How safe is that?

Fact versus fiction is a scary line to smear for the sake of business. I suggest doctors, diabetes educators, and patients review the facts today and compare it to the propaganda in the 80s. There is no suppressing the truth!

A recent study found that 87% of patients who experienced an adverse symptom from a prescribed drug spoke to their doctor. However less than half of the doctors went through with filing the adverse event paperwork to notify the drug manufacturer. Why is this?

The research was published in the latest issue of Drug Safety. Doctors dismissed patients' complaints, and told them their symptoms were not connected to use of the drug. One doctor commented that the time it takes to complete the adverse event drug paperwork is time-consuming, and often not worth it unless it is life threatening. Would Hippocrates have accepted that answer? Please review your Hippocratic Oath, doc.

Your doctor is too busy to file the necessary paperwork to notify the FDA a drug is potentially harmful. What is a patient to do? Good question and here's an answer! If you experienced any adverse side effects from the use of a prescription drug, please let the FDA know. Click BEGIN and bring this monkey business to an end!

Nutrigenetics is the study of the interaction of genes and diet. The Diet Channel has published an article explaining what nutrigenetics is and how it will revolutionize the world of diabetes.

Researchers believe elevated blood sugar can be mapped back to a genetic reaction. Drugs are only overriding the cause of elevated blood sugar and forcing the sugar into the cells, causing damage over time. Nutrigenetics is addressing the cause of the elevated blood sugar and may suggest a better diet to control your diabetes. Genes control how you metabolize certain vitamins, minerals, and nutrients. These genes can vary from one individual to the next. See what happens to Buddy the Elf when he consumes way too much coffee? Yes, I know - that's Hollywood. Nevertheless - a comical example of what nutrigenetics explores.

Consumer-friendly tests are available for these gene and diet interactions. The tests are done with a cheek swab. You send your swab off to a specialized lab, which analyzes DNA from the cheek cells. You receive a report identifying your gene variations. A qualified health professional can explain the test results, and make specific diet and supplement recommendations to optimize your health. If this is a test you're interested in taking, Sciona's Mycellf Program will be happy to prepare your profile. Open up and say Ahhhh.

A study reported in the journal Nutrition found obese, diabetic mice whose diet was supplemented with an extract of cacao liquor demonstrated a significant reduction in blood sugar.

Scientists examined if cacao beans might be helpful in preventing Type 2 diabetes. They supplemented the diets of obese, diabetic mice with cacao liquor for 3 weeks. The specific type of cacao liquor, called cacao liquor proanthocyanidins (CLPr), contains 72% polyphenols. They found that blood sugar was reduced in direct correlation with the dosage of CLPr.

This study was funded by confectionary giant Mars, Inc. In case Mars doesn't ring a bell - maybe some of their products might: Snicksers, 3 Musketeers, Milky Way, and M & M's to name a few. With the results of this research, and the deep pockets behind it -- maybe Mars is contemplating coming out with a diabetes-reversing candy bar? I suggest they call it The Sweet Escape (start the music!)

Aaaahh ... fall will soon deliver golden trees, crisp autumn air, piles of fallen leaves begging to be jumped in, and the stick of the flu vaccine.

The National Foundation for Infectious Diseases (NFID) recently issued a report calling for greater influenza vaccination rates among Americans with diabetes. Turns out more than 50 percent of the 21 million people with diabetes do not receive an annual influenza vaccination. This is contrary to the recommendations of the Centers for Disease Control and the American Diabetes Association.

According to Dr. William Schaffner, NFID's vice president, the impaired immune systems of people with diabetes can result in a higher risk of serious complications from influenza, including impaired blood sugar control. Annually, this infectious disease strikes up to 60 million Americans and kills an average of 36,000 people -- more than all other vaccine-preventable diseases combined. Over 10 percent of deaths linked to influenza and pneumonia are due to diabetes. There are studies citing the benefits of the vaccine for people with diabetes, including reduced hospitalization and death by 72 percent for those with diabetes 18 to 64 years of age, and 80 percent less hospital admissions for children and adults with diabetes.

I'm just speculating, but lack of awareness, lack of access to an affordable vaccine or just plain philosophical disagreement with the need for the vaccine (among other factors) may all play a role in the low influenza vaccination rates for people with diabetes. Just an example, my parents both have type 1, and my mom will stand in line for hours to get a shot (she was hospitalized for influenza in her pre-diabetes days), while my dad always refuses -- he's never had influenza. Read more at Infection Control Today.

Jennifer Ordoñez, a Newsweek journalist who is also a Type 1 diabetic, reported on her experience at a triathlon training camp geared for diabetics. After reading her report, I was curious as to why hypoglycemia would cause a diabetic to fail the VO2 max test.

Nobody likes failing tests - especially when it comes to something as important as VO2 max. VO2 max is the maximum amount of oxygen a person uses while exercising at their limit for one minute. If you are in shape, your muscles will use a lot of oxygen to create energy. The prime source of energy for the body comes from blood sugar. When Jennifer took her VO2 test her blood sugar was falling and she failed. Apparently when blood sugar is falling the body puts itself into energy lockdown which compromises even conditioned athletes VO2 max.

Hypoglycemia causes muscles to fatigue quicker. Muscle fatigue is the result of inadequate oxygen availability. Prevention of hypoglycemia is one of the major objectives of adequate blood sugar when you are about to work out. By maintaining optimal blood sugar, you can assure a better level of exercise performance. I know better than to tell you what to do. But as a friendly reminder: make sure you've fueled up adequately before you hit the gym or the open road to work on your VO2 max.

Back in 2000, researchers at the University of Alberta in Edmonton, Canada transplanted islet cells in the livers of people with type 1, known as the Edmonton Protocol. Each islet transplant required several cadaver donors. The transplants worked for awhile, but approximately 80 percent of patients required insulin after a couple years. It was assumed the transplanted cells were rejected, but new research points to a new possible culprit -- fat.

Dr. Roger Unger and colleagues of the University of Texas Southwestern Medical Center in Dallas performed the Edmonton Protocol in rats with type 1. Fat built up around the transplanted cells in only a month. The cells stopped producing insulin and the rats died after 15 weeks. Dr. Unger explained the liver creates fatty acids from food, and islet transplants in the liver are surrounded by too much fat. He proved his point by repeating the transplant in a separate group of type 1 rats, but this time the rats were on a strict diet. A third group of rats received leptin, a hormone involved in increasing metabolism and decreasing appetite. These rats had an improved response, although the Reuters story does not provide specifics. Here's the study abstract in Diabetes, but ya gotta pay for the full text article.

Bummer. You get an islet cell transplant, but still have to stay away from the Ben & Jerry's. A next step could be testing this theory in human islet cell transplants via a low-calorie, low-sugar diet following transplantation. Read more in Reuters.

New research finds tuberculosis (TB) is more difficult to treat if the patient has type 2 diabetes. The study examined 737 Indonesians with tuberculosis screened for type 2. Nearly 15 percent had type 2, and initially, their TB was as severe as the non-diabetics. After two months of treatment, TB sputum tests were positive 18.1 percent for those with type 2 and only 10 percent in non-diabetics. At the six month mark, 22.2 percent of type 2s had positive sputum results compared to 9.5 percent of the non-diabetics.

The story in Reuters does not address why people with TB and type 2 diabetes do not respond as well to TB treatment. Tuberculosis is a serious infectious disease. Over one-third of the world carries the TB bacterium, and one in ten latent infections will progress to active TB disease. Untreated, active TB is a real threat, it kills more than half of its victims. Experts are examining how rising rates of type 2 are impacting TB control and prevention worldwide.

I just finished reading an excellent book about Dr. Paul Farmer's inspirational work treating tuberculosis in impoverished communities worldwide -- Mountains Beyond Mountains: The Quest of Dr. Paul Farmer, A Man Who Would Cure the World -- masterfully written by Tracy Kidder. I wonder what Dr. Farmer has to say about people with type 2 and TB.

When I read the headline in this Yahoo! news, Obesity rates climb in most states, I took a stab at guessing the leanest and fattest states in America. My favorite state, Colorado, immediately came to mind for the fittest state. Ding, ding, ding ... that is correct! But I had no clue on the fattest state, West Virginia was a shaky guess. I heard the buzzer on that one, Mississippi became the first state to break the 30 percent barrier for obese, adult residents. But hey, I wasn't far off, West Virginia and Alabama are slightly behind the double-letter state.

Colorado has an obesity rate of 17.6. Yikes, this is the leanest state in the nation. Statistics were provided by the Trust for America's Health. They analyzed state health department-generated telephone surveys of height and weight, combining three years of data (2004-2006) for improved projections. No one denies obesity increases the risk for diabetes and chronic diseases. Jeffrey Levi, executive director, stated everyone believes obesity is an epidemic, but political and policymaker attention is lacking. Levi agrees weight is a personal choice and responsibility, but he wants societal improvements to help people make better choices, such as healthier school lunches and safer places to be active across all classes.

The report is not intended to stigmatize fat states, but motivate them to action. Is this honestly a good way to do it? We should be talking about poverty in Mississippi, not scolding them. The five poorest states were in the top 10 when it came to obesity rates. I'm sure the Mississippi fat jokes have already begun. This country loves to categorize, from Money's Best Places to Live to U.S. News & World Report's America's Best Colleges. Now we'll be adding an obesity category to all these reports. I can see it now, some diet rag will announce the Top 100 Thinnest Universities.