Why is hindsight 20/25 in diabetes?
Posted Aug 27th 2007 10:03AM by Allie Beatty
Filed under: Type 1, Type 2, Childhood, Adult Onset, Drugs, Research, Opinion, Allie Beatty, Support
Bev did a great job covering the study of obese mice having protection from elevated blood sugar due to a plethora of adiponectin. Adiponectin was shown to enhance insulin signaling which transported the excess glucose to less harmful areas of the body, rather than the cells which would endure diabetes complications. The results of this study created a condition called ratones mórbidamente obesos - which sounds better in Spanish because in English this means morbidly obese mice.
You know what they say about hindsight, right? A study from a year ago revealed some good news and some bad news. Good news first - turns out Type 2 diabetes drugs using troglitazone increased adiponectin. Rezulin was one of these drugs, but it was removed from the US market March 21, 2000. Now the bad news, the Type 2 diabetes drugs made with metformin were shown to reduce adiponectin. A few of the drugs that use metformin are Fortamet, Glucophage, Glucophage XR, and Riomet.
So why must diabetics be led with imperfect vision? Because the bottom line is researchers and doctors believe they are saving lives every day. Yes, they do. But there is a lot to behold when you tinker with His design. Remember the movie Malice? These lines don't make it into movies for nothing. Producers know human nature and they stretch it to the extreme. Whether or not you want to admit it - you know a few people with a complex like Alec Baldwins. Alec Baldwin says, "You ask me if I have a God complex. Let me tell you something: I am God". Click for the entire 1:30 scene, courtesy of YouTube.
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1. What we then need is:
1. Adiponectin sold separately for people with IRD(aka Type 2 Diabetes)
2. C-peptide for T1DM
All the above can be made available and should be in the Marketplace ASAP. Isn't it cheaper to prevent Complications than to treat them after they have already occurred?
Posted at 10:58AM on Aug 27th 2007 by BetterCell