Less insulin longer life
Posted Jul 21st 2007 3:20PM by Allie Beatty
Filed under: Type 1, Type 2, Childhood, Adult Onset, Diet, Research
Howard Hughs Medical Experts have discovered the key to a longer life is lower insulin levels. Less insulin helps cells fend off diseases that lead to early death like heart disease, cancer and diabetes. So how does one lower their insulin levels? Caloric restriction by way of eating less carbohydrates.
Caloric restriction postpones the onset of life-threatening conditions like cancer, diabetes, and heart disease. It may still happen, but at a later age. Scientists manipulated genes in mice to produce 50% less insulin and saw the mice live 18% longer. While lowering insulin throughout the body can lead to a diabetic state, scientists found that allowing insulin levels to be high throughout most of the body, and lowering the insulin signaling only in the brain through genetic manipulation, extended the life of mice.
Although the mice were overweight, they lived longer and seemed active and youthful. Scientists believe that this research explains why some people who live past 100 may have a natural genetic tendency for lower insulin signaling in the brain. They eat a normal amount of calories and may even be a bit overweight, but still enjoy the benefit of life extension. This begs the question: if all diabetes oral meds multiply the effect of insulin -- doesn't this increase the chances of heart disease and cancer? New Rule: Black box warning on ALL prescription diabetes drugs!!
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1. "Howard Hughs Medical Experts have discovered the key to a longer life is lower insulin levels."
Would this ALSO apply to those of us with T1DM who rely on exogenous insulin?
Of course the only way to reduce the amount of exogenous insulin would also be a reduction in carbohydrate intake along with exercise.
What are your feelings regarding this(Howard Hughs study) as being applicable to T1DM?
Posted at 4:44PM on Jul 21st 2007 by BetterCell