A glucosamine-like dietary supplement has been found to suppress the damaging autoimmune response seen in type 1 diabetes, according to University of California, Irvine health sciences researchers.
In studies on mice, researchers found that N-acetylglucosamine (GlcNAc), which is similar but more effective than the widely available glucosamine, inhibited the growth and function of hyperactive T-cells that cause diabetes. GlcNAc increased sugar modifications to the T-cell proteins, preventing the hyperactive immune response. This therapy normalized T-cell functions and prevented development of high blood glucose levels in type 1 diabetes.
GlcNAc decreases pain and inflammation, which likens the results of the Irvine study to a study that was conducted in Toronto last December. Researchers found they were able to cure diabetic mice overnight by injecting them with something called Substance P. Substance P is involved in the transmission of pain impulses from peripheral receptors to the central nervous system. Diabetes is like a rat without the ability to feel pain. The naked mole rat lacks Substance P and cannot feel pain when painful stimuli are administered to the skin. Snapple fact, folks!











1. I wonder Allie, if OUR Immune System is always "looking" for things within our body to suppress and destroy.
If that is the case, then having an Auto-Immune Illness is never gone even after the Disease(T1DM) has been created.
Maybe that is why, that many people with T1DM also have "other" Illnesses as well, such as Thyroid Disease.
If acetylglucosamine could stop this proclivity in those with T1DM then it is worth an investigation and use as an additional supplement w/o Pharmaceuticals getting involved.
Posted at 10:13AM on Jun 10th 2007 by BetterCell